Cryopreservation of Oocytes Retrieved from Ovarian Tissue to Optimize Fertility Preservation in Prepubertal Girls and WomenSophie Brouillet 1,2, Alice Ferrieres-Hoa 2, Alice Fournier 2, Guillaume Martinez 3, Julien Bessonnat 3, Aurore Gueniffey 3, Anna Gala 2, Vanessa Loup 2, Samir Hamamah 1,2
1Développement Embryonnaire Précoce Humain et Pluripotence, Univ Montpellier, INSERM 1203, 2Département de Biologie de la Reproduction, Biologie de la Reproduction/DPI et CECOS, CHU Montpellier, Univ Montpellier, 3Centre d'AMP-CECOS, CHU Grenoble-Alpes, Univ Grenoble-Alpes
We propose a protocol for fertility preservation in prepubertal girls and women at risk of premature ovarian insufficiency. It combines ovarian tissue freezing and cryopreservation of oocytes retrieved from ovarian tissue. This strategy improves the safety and optimizes the reproductive potential of fertility preservation, maximizing the chance of childbirth.