High-Throughput Bioprinting Method for Modeling Vascular Permeability in Standard Six-well Plates with Size and Pattern FlexibilityAshfaq Ahmad 1,2, Mst Zobaida Akter 1,2, Seo-Yeon Kim 1,2, Yeong-Jin Choi 3,4, Hee-Gyeong Yi 1,2
1Department of Convergence Biosystems Engineering, College of Agriculture and Life Sciences (CALS), Chonnam National University, 2Interdisciplinary Program in IT-Bio Convergence System, Chonnam National University, 3Advanced Bio and Healthcare Materials Research Division, Korea Institute of Materials Science (KIMS), 4Advanced Materials Engineering, Korea National University of Science and Technology (UST)
We present a protocol for high-throughput production of vascular channels with flexible sizes and desired patterns on a standard six-well plate using 3D bioprinting technology, referred to as vessels-on-a-plate (VOP). This platform has the potential to advance the development of therapeutics for the disorders associated with compromised endothelium.