Sidney Kimmel Comprehensive Cancer Center

1 ARTICLES PUBLISHED IN JoVE

Cancer Research

Use of Micropipette-Guided Drug Administration as an Alternative Method to Oral Gavage in Rodent Models

Angélica Cruz Lebrón¹, Emily Blackwell^1,2, Pedro Balbuena Almodóvar¹, Tasnim Syakirah Faiez¹, Luke A. Mummert¹, Karen S. Sfanos^1,3,4

¹Department of Pathology, Johns Hopkins University School of Medicine, ²Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, ³Sidney Kimmel Comprehensive Cancer Center, ⁴Department of Urology, Johns Hopkins University School of Medicine

Here, we describe micropipette-guided drug administration (MDA) as an alternative method to oral gavage that incentivizes the research animal to ingest treatments readily with minimal stress and discomfort.