In vivo Imaging and Therapeutic Treatments in an Orthotopic Mouse Model of Ovarian CancerAlexis B. Cordero 1, Youngjoo Kwon 1, Xiang Hua 2, Andrew K. Godwin 1
1Department of Medical Oncology, Women's Cancer Program, 2Transgenic Mouse Facility, Fox Chase Cancer Center
Orthotopic animal models of ovarian cancer replicate better human disease and therefore enhance our understanding of cancer progression and tumor response to therapy. A mouse model receives an intrabursal injection of luciferase-expressing ovarian tumor cells. Treatment is administered via oral gavage. Tumor growth is monitored by in vivo imaging system.
