MIA Adult Offsrping Behavioral Abnormality Evaluation
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Results: MIA Adult Offsrping Exhibit Abnormalities Associated with Autism and Schizophrenia
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Conclusion
Trascrizione
The overall goal of this procedure is to induce maternal immune activation, or MIA, in mice by intraperitoneal injection of the viral mimic poly at the mid-gestational embryonic stage. This method can help us answer key questions in a neuro-immuno
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Maternal immune activation (MIA) is a model for an environmental risk factor of autism and schizophrenia. The goal of this article is to provide a step-by-step procedure of how to induce MIA in the pregnant mice in order to enhance the reproducibility of this model.