Results: H&E Longitudinal Sections of Sciatic Nerves Injected with Panc02H7 Cancer Cells in Wild Type and NCAM KO Mice
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Conclusion
Trascrizione
The overall goal of this surgical procedure is to create an in vivo model of perineural invasion by injecting cancer cells into the sciatic nerve of mice. Perineural invasion is the invasion of nerves found in many cancer types This method can hel
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We describe an in vivo murine model of perineural invasion by injecting syngeneic pancreatic cancer cells into the sciatic nerve. The model allows for quantification of the extent of nerve invasion, and supports investigation of the cellular and molecular mechanisms of perineural invasion.