Results: Environmental Manipulations Modify Relapse in Cocaine Seeking in Mice
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Conclusion
Trascrizione
The overall goal of this procedure is to evaluate reinstatement of drug-seeking behavior in laboratory animals considering the impact of the drug associated environmental cues and stress. This method can help answer key question in the drug addict
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This protocol describes the Conditioned Place Preference (CPP) as a model of relapse. This procedure permits the measurement of relapse in laboratory animals, considering the impact of drug-associated environmental cues as craving and relapse in abstaining addicts is currently the focus of drug-abuse treatment programs.