This method can help answer key questions in the field of antibiotic resistance about novel therapeutics with a treatment of ventilator-associated pneumonia. The main advantage of this technique is that it accurately replicates clinical infection
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Infectious pneumonia is among the most common infections in human. An appropriate in vivo model is critical for understanding disease pathogenesis and testing the efficacy of novel therapeutics. With this murine oropharyngeal aspiration pneumonia model, one can examine the pathogenesis and new treatments against these deadly infections.