Triggering a Closed-Loop Stimulation by Neuron Spiking Activity

To perform a closed-loop experiment, resume the data acquisition in Cheetah and open Matlab. Open ClosedLoop.m and click Run. Alternatively, execute ClosedLoop in the command window. Browse to the recording folder, and select one of the spiking data files to load the spike information defined in the initial recording. Click the appropriate checkboxes under the plotted waveforms to select one or multiple neurons that will trigger stimulation.

Define the minimum number of neurons that will trigger stimulation by entering an integer in the Min Matches text box, and define the time window in which the spikes matching the different waveforms are considered co-active by entering a number into the Window text box. Then, click Send to begin the online triggering of events based on the spiking activity of the selected neurons.