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In This Article

  • Summary
  • Abstract
  • Introduction
  • Protocol
  • Representative Results
  • Discussion
  • Acknowledgements
  • Materials
  • References
  • Reprints and Permissions

Summary

Acupoint application combined with acupressure-assisted treatment has a good effect on chemotherapy-induced nausea and vomiting and is more convenient and cost-effective.

Abstract

Chemotherapy-induced nausea and vomiting (CINV) refers to the nausea and vomiting experienced by patients after the application of chemotherapy drugs, significantly affecting their quality of life and physical recovery, as well as increasing the pain of the patients. Basic medicine primarily focuses on acid suppression, gastric protection, and vomiting suppression, but there are still many patients with nausea and vomiting symptoms that cannot be alleviated. Traditional Chinese medicine (TCM) can effectively alleviate nausea and vomiting through acupoint stimulation and pressure, while also offering advantages such as simplicity, affordability, and fewer side effects. The aim of this article is to introduce the method of using acupoint application combined with acupressure as an adjunctive therapy for CINV, using the Multinational Association of Supportive Care in Cancer (MASCC) Antiemesis Tool (MAT) tablet scale as a questionnaire. The article details aspects such as acupoint selection, production, and the use of acupoint application, massage techniques, and operating procedures, all with the goal of ensuring the safety and efficacy of acupoint application combined with acupressure as an adjuvant therapy, thereby improving patients' clinical symptoms and quality of life.

Introduction

Chemotherapy, as one of the important methods for treating cancer, treats tumors while also imposing various side effects on patients. Chemotherapy-Induced Nausea and Vomiting (CINV) refers to the symptoms of nausea and vomiting that occur after a patient receives chemotherapy drugs. Nausea is a subjective sensation of uneasiness in the epigastrium or throat, often accompanied by an impending sense of vomiting. Vomiting involves the ejection of stomach contents through the mouth. Both nausea and vomiting can happen simultaneously or independently, with nausea being more frequently experienced than vomiting among chemotherapy patients1. Affectin....

Protocol

Trial data were collected from a randomized controlled experiment conducted on chemotherapy patients in the Oncology Department of Chengdu First People's Hospital. This trial follows the Helsinki Declaration and was approved by the Oncology Department of Chengdu First People's Hospital, with proper documentation within the department. Patients received relevant trial information and signed informed consent was collected prior to trial commencement.

1. Patient selection

Representative Results

A clinical trial was conducted involving 12 patients receiving chemotherapy at the First People's Hospital of Chengdu for oncology treatments between January and February 2024. A total of 12 patients receiving chemotherapy were included in this study, of which 8 were male, accounting for 66.6%, and 4 were female, accounting for 33.3%. Of the 12 patients receiving chemotherapy, six were in the control group and six in the treatment group. The statistical analysis of weight and height between the treatment group and th.......

Discussion

Numerous cancer patients, such as those with breast cancer, lung cancer, prostate cancer, or hematological malignancies, commonly endure nausea and vomiting during chemotherapy. This unpleasant experience can lead to decreased appetite, inadequate nutrition intake, and poor physical condition, negatively impacting the overall treatment outcome. It also reduces patient adherence to therapy and fosters fear towards chemotherapy9. In over three decades of research, it has been found that the 5-HT3 re.......

Acknowledgements

We acknowledge the financial support from the 'Scholar of XingLin' Discipline Talent Research Enhancement Program of Chengdu University of Traditional Chinese Medicine (Grant No. XKTD2022014).

....

Materials

NameCompanyCatalog NumberComments
Acupoint application for external use breathable adhesive applicationHoly Royal HallLu 's standard 20152090318Encapsulate traditional Chinese medicine paste and fix it on specific human skin.
Chinese herbal medicine superfine grinding machineYongkang Sufeng Industry & Trade Co., Ltd.YB-2500A Grinding Chinese medicine into powder
disinfection alcoholZhejiang Prokonyu Pharmaceutical Co., Ltd.CYHB2101229GBPovidone iodine aqueous solution has no disadvantages of iodine tincture, light coloring, easy elution, small stimulation to mucosa, no need for ethanol deiodination, no corrosion effect, and low toxicity.
Medical VaselineDezhou Yile Disinfection Technology Co., Ltd.Lu Weixiao Certificate ( 2020 ) No. 1363This product is suitable for the preparation of ointment matrix, used as lubricant, waterproof agent, can also be used for precision instrument maintenance
medical rubber gloveJiangsu Huicheng Medical Technology Co., Ltd.National Machinery No.20160956Disposable latex gloves
medical absorbent cottonHebei Kangji Pharmaceutical Co., Ltd.Ji mechanical injection20192140019medical absorbent cotton
medical bowlChaozhou Caitang Town Yuekang Hardware Medical Treatment201/304Store acupoint application
Medical bending plateShenzhen Defu Medical Device Co., Ltd.DF-238Put cotton swabs, stickers, gloves and other items.
rinse-free hand sanitizerAnhui Qicheng Biotechnology Co., Ltd.Wanwei Xiaozhengzi 2019 No. A0009For operator hand disinfection
 SPSS statisticsIBMIBM spss statistics 25IBM SPSS Statistics supports a top-down, hypothesis testing approach to your data
Saline 100 mLShandong Qidu Pharmaceutical Co., Ltd.Luzi Pharmaceutical Supervision Machinery Production Preparation No.202300030.9 % physiological saline-sterile for the preparation of traditional Chinese medicine powder
traditional chinese medicinal herbs
20 g of ginger 20 g of clove
20 g of nutmeg
20 g of Kaki calyx
20 g of Aucklandia lappa
Hongya County Wawushan Pharmaceutical Co., Ltd.23020 Acupoint application of traditional Chinese medicine powder

References

  1. Singh, P., Yoon, S. S., Kuo, B. Nausea: a review of pathophysiology and therapeutics. Ther Adv Gastroenterol. 9 (1), 98-112 (2016).
  2. Ballatori, E., et al. The impact of chemotherapy-induced nausea and vomiting on....

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Chemotherapy induced Nausea And VomitingAcupoint ApplicationAcupressureTraditional Chinese MedicineAdjunctive TherapyMASCC Antiemesis Tool

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