Irina Pokrovskaya

Nuclear UDP-glucuronosyltransferases: identification of UGT2B7 and UGT1A6 in human liver nuclear membranes.

The translational regulation of lipoprotein lipase by epinephrine involves an RNA binding complex including the catalytic subunit of protein kinase A.

Role of A kinase anchor proteins in the tissue-specific regulation of lipoprotein lipase.

The lipogenic enzymes DGAT1, FAS, and LPL in adipose tissue: effects of obesity, insulin resistance, and TZD treatment.

Translational regulation of lipoprotein lipase in adipocytes: depletion of cellular protein kinase Calpha activates binding of the C subunit of protein kinase A to the 3'-untranslated region of the lipoprotein lipase mRNA.

Adiponectin translation is increased by the PPARgamma agonists pioglitazone and omega-3 fatty acids.

The COG complex, Rab6 and COPI define a novel Golgi retrograde trafficking pathway that is exploited by SubAB toxin.

Conserved oligomeric Golgi complex specifically regulates the maintenance of Golgi glycosylation machinery.

The lipoprotein lipase (LPL) S447X gain of function variant involves increased mRNA translation.

COG6 interacts with a subset of the Golgi SNAREs and is important for the Golgi complex integrity.

COG complexes form spatial landmarks for distinct SNARE complexes.

Fluorescent microscopy as a tool to elucidate dysfunction and mislocalization of Golgi glycosyltransferases in COG complex depleted mammalian cells.

Cog5-Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex.

STEM tomography reveals that the canalicular system and α-granules remain separate compartments during early secretion stages in blood platelets.

COG Complex Complexities: Detailed Characterization of a Complete Set of HEK293T Cells Lacking Individual COG Subunits.

Golgi proteins in circulating human platelets are distributed across non-stacked, scattered structures.

Membrane detachment is not essential for COG complex function.

More than just sugars: Conserved oligomeric Golgi complex deficiency causes glycosylation-independent cellular defects.

Alterations in platelet secretion differentially affect thrombosis and hemostasis.

SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets.

Autophagy in Platelets.

Defects in COG-Mediated Golgi Trafficking Alter Endo-Lysosomal System in Human Cells.

3D ultrastructural analysis of α-granule, dense granule, mitochondria, and canalicular system arrangement in resting human platelets.

Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis.

Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape.

Platelet α-granule cargo packaging and release are affected by the luminal proteoglycan, serglycin.

Dense cellular segmentation for EM using 2D-3D neural network ensembles.

Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates.

Development and Initial Characterization of Cellular Models for COG Complex-Related CDG-II Diseases.

Acute COG complex inactivation unveiled its immediate impact on Golgi and illuminated the nature of intra-Golgi recycling vesicles.

High-Pressure Freezing Followed by Freeze Substitution: An Optimal Electron Microscope Technique to Study Golgi Apparatus Organization and Membrane Trafficking.

Rapid COG Depletion in Mammalian Cell by Auxin-Inducible Degradation System.

GARP dysfunction results in COPI displacement, depletion of Golgi v-SNAREs and calcium homeostasis proteins.

Tethered platelet capture provides a mechanism for restricting circulating platelet activation to the wound site.

Syntaxin-5's flexibility in SNARE pairing supports Golgi functions.

A missense mouse model for Smith-McCort dysplasia shows bone resorption defects and altered protein glycosylation.

Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets.

Essential role of the conserved oligomeric Golgi complex in .