Julie A. Hixon

Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut.

Synergistic engagement of an ineffective endogenous anti-tumor immune response and induction of IFN-gamma and Fas-ligand-dependent tumor eradication by combined administration of IL-18 and IL-2.

IL-27 mediates complete regression of orthotopic primary and metastatic murine neuroblastoma tumors: role for CD8+ T cells.

Therapeutic modulation of Akt activity and antitumor efficacy of interleukin-12 against orthotopic murine neuroblastoma.

Multicolor fluorescence-based approaches for imaging cytokine-induced alterations in the neovascularization, growth, metastasis, and apoptosis of murine neuroblastoma tumors.

Proteasome inhibition to maximize the apoptotic potential of cytokine therapy for murine neuroblastoma tumors.

Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP.

Immunologic and therapeutic synergy of IL-27 and IL-2: enhancement of T cell sensitization, tumor-specific CTL reactivity and complete regression of disseminated neuroblastoma metastases in the liver and bone marrow.

Visualization and identification of IL-7 producing cells in reporter mice.

Interleukin-7 regulates Bim proapoptotic activity in peripheral T-cell survival.

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.

High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery.

HIV immune activation drives increased Eomes expression in memory CD8 T cells in association with transcriptional downregulation of CD127.

Oral Delivery of IL27 Recombinant Bacteria Attenuates Immune Colitis in Mice.

Adaptive immunity to murine skin commensals.

IL-22-Expressing Murine Lymphocytes Display Plasticity and Pathogenicity in Reporter Mice.

Development and Preclinical Application of an Immunocompetent Transplant Model of Basal Breast Cancer with Lung, Liver and Brain Metastases.

Mutant IL-7Rα and mutant NRas are sufficient to induce murine T cell acute lymphoblastic leukemia.

IL-7-induced phosphorylation of the adaptor Crk-like and other targets.

Inhibiting Janus Kinase 1 and BCL-2 to treat T cell acute lymphoblastic leukemia with IL7-Rα mutations.

New anti-IL-7Rα monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.

Mutations that collaborate with IL-7Ra signaling pathways to drive ALL.

IL-7: Comprehensive review.

A Focused Review of Ras Guanine Nucleotide-Releasing Protein 1 in Immune Cells and Cancer.

IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium.