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Hebrew University Medical School

1 ARTICLES PUBLISHED IN JoVE

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Immunology and Infection

Isolation and Characterization of Neutrophils with Anti-Tumor Properties
Ronit Vogt Sionov 1, Simaan Assi 1, Maya Gershkovitz 1, Jitka Y. Sagiv 1, Lola Polyansky 1, Inbal Mishalian 2, Zvi G. Fridlender 2, Zvi Granot 1
1Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Hebrew University Medical School, 2Institute of Pulmonary Medicine, Hadassah-Hebrew University Medical Center

Neutrophils play an important role not only in host defense against invading microorganisms, but are also involved in the immune surveillance of tumor cells. Here, we describe techniques related to the isolation of neutrophils with anti-tumor properties and methods for monitoring anti-tumor neutrophil function in vitro and in vivo.

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