JoVE Logo

Sign In

Hospital Universitario La Paz

1 ARTICLES PUBLISHED IN JoVE

image

Biology

A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection
Silvia Murillo-Cuesta *1,2,3, Néstor Vallecillo *1, Rafael Cediel 1,2,4, Adelaida M. Celaya 1,2, Luis Lassaletta 3,5, Isabel Varela-Nieto 1,2,3, Julio Contreras 1,2,4
1Instituto de Investigaciones Biomédicas (IIBm) Alberto Sols CSIC-UAM, 2Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III (ISCIII), 3Instituto de Investigación Sanitaria La Paz (IdiPAZ), 4Facultad de Veterinaria, Universidad Complutense de Madrid, 5Departmento de Otorrino laringología, Hospital Universitario La Paz

Two microsurgery approaches for local drug delivery to the inner ear are described here and compared in terms of impact on hearing parameters, cochlear cytoarchitecture and expression of inflammatory markers.

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved