Precise Cellular Ablation Approach for Modeling Acute Kidney Injury in Developing ZebrafishRohan Datta 1, Ada Wong 1, Troy Camarata 2, Farhana Tamanna 1, Imran Ilahi 1, Aleksandr Vasilyev 1
1Department of Biomedical Sciences, NYITCOM, 2Department of Basic Sciences, NYITCOM-A-State
This work presents a new in vivo model of segmental kidney injury using kidney GFP transgenic zebrafish. The model allows for the induction of the targeted ablation of kidney epithelial cells to show the cellular mechanisms of nephron injury and repair.
