University of Campania "Luigi Vanvitelli"

1 ARTICLES PUBLISHED IN JoVE

Developmental Biology

HUVEC Tube-formation Assay to Evaluate the Impact of Natural Products on Angiogenesis

Maria Teresa Gentile¹, Olga Pastorino¹, Maurizio Bifulco², Luca Colucci-D'Amato¹

¹Laboratory of Cellular and Molecular Neuropathology, Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", ²Department of Molecular Medicine and Biotechnologies, University of Naples "Federico II" Naples

Here, we evaluate the effects of the water extract of Ruta graveolens on vessel network formation by using a tube formation assay on a gelled basement matrix.