The overall goal of this technique is to measure how nematodes and their neurons respond to external mechanical stimuli using a microfluidic chip setup with pressure actuators. This method can answer key questions in the fields of mechanobiology a
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New tools for mechanobiology research are needed to understand how mechanical stress activates biochemical pathways and elicits biological responses. Here, we showcase a new method for selective mechanical stimulation of immobilized animals with a microfluidic trap allowing high-resolution imaging of cellular responses.