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High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor

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09:16 min

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June 14th, 2018

DOI :

10.3791/57374-v

June 14th, 2018

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9,742 Views

Yu Okazawa^1,2, Kosuke Mizukoshi^1,2, Yu Koyama^2,4, Shoki Okubo⁵, Hiromitsu Komiyama¹, Yutaka Kojima¹, Michitoshi Goto¹, Sonoko Habu³, Okio Hino², Kazuhiro Sakamoto¹, Akira Orimo²

¹Department of Coloproctological Surgery, Juntendo University Faculty of Medicine, ²Department of Molecular Pathogenesis, Juntendo University Faculty of Medicine, ³Atopy Research Center, Juntendo University Faculty of Medicine, ⁴Department of Oral Pathobiological Science and Surgery, Tokyo Dental College, ⁵Department of Gastroenterology, Juntendo University Faculty of Medicine

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Keywords Micrometastases

Patient derived Colon Tumor

Organoid Culture

Extracellular Matrix

Colorectal Cancer

Tumor Xenograft

Cell Dissociation

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