Results: Representative Tau Subcellular Enrichment Analyses
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Conclusion
필기록
This method can help answer key questions about the direct role of tau in the nuclear compartment while excluding any potential cytoplasmic tau contamination. The main advantage of this technique is that it is broadly applicable to the study on th
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Tau is a neuronal protein present both in the cytoplasm, where it binds microtubules, and in the nucleus, where it exerts unconventional functions including the modulation of Alzheimer's disease-related genes. Here, we describe a method to investigate the function of nuclear Tau while excluding any interferences coming from cytoplasmic Tau.