Preparation of Experimental Setup and Induction of Mild TBI in Rodents
3:06
Exposure of Rodent to Blast Wave and its Recovery
3:59
Results: Acute In-Vivo Effects of Blast-Induced TBI
5:28
Conclusion
필기록
This protocol produces a non-invasive closed-head brain injury that recapitulates the human experience of a sports injury or blast exposure in the open field. The primary advantage of this protocol is that allows for movement of the head in order
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We present here a protocol of a blast wave model for rodents to investigate neurobiological and pathophysiological effects of mild to moderate traumatic brain injury. We established a gas-driven, bench-top setup equipped with pressure sensors allowing for reliable and reproducible generation of blast-induced mild to moderate traumatic brain injury.