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Sha Huang

Department of Internal Medicine,
Division of Gastroenterology,
Department of Internal Medicine, Division of Gastroenterology

University of Michigan

BIOGRAPHY

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PUBLICATIONS

Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.

Protein science : a publication of the Protein Society Aug, 2007 | Pubmed ID: 17656578

Mechanism of LDL binding and release probed by structure-based mutagenesis of the LDL receptor.

Journal of lipid research Feb, 2010 | Pubmed ID: 19674976

Huntingtin-interacting protein 1 phosphorylation by receptor tyrosine kinases.

Molecular and cellular biology Sep, 2013 | Pubmed ID: 23836884

Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice.

Gastroenterology Oct, 2013 | Pubmed ID: 23860500

Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function.

Infection and immunity Jan, 2015 | Pubmed ID: 25312952

Intestinal organoids: a model of intestinal fibrosis for evaluating anti-fibrotic drugs.

Experimental and molecular pathology Jun, 2015 | Pubmed ID: 25828392

Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids.

Biology open Oct, 2015 | Pubmed ID: 26459240

LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation.

Cellular and molecular gastroenterology and hepatology Sep, 2016 | Pubmed ID: 28078320

Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine.

Stem cell reports Sep, 2017 | Pubmed ID: 28803915

Synthetic hydrogels for human intestinal organoid generation and colonic wound repair.

Nature cell biology Nov, 2017 | Pubmed ID: 29058719

Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.

Proceedings of the National Academy of Sciences of the United States of America Nov, 2017 | Pubmed ID: 29078383

Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium.

eLife Nov, 2017 | Pubmed ID: 29110754

INSTITUTIONS

University of Michigan

JOVE ARTICLES

Real-time Measurement of Epithelial Barrier Permeability in Human Intestinal Organoids

David R. Hill¹,

Sha Huang¹,

Yu-Hwai Tsai¹,

Jason R. Spence^1,2,

Vincent B. Young^1,3

¹Department of Internal Medicine, Division of Gastroenterology, University of Michigan,

²Department of Cell and Developmental Biology, University of Michigan,

³Department of Internal Medicine, Division of Infectious Disease, University of Michigan

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Sha Huang

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Internal Medicine,Division of Gastroenterology,Department of Internal Medicine, Division of Gastroenterology

University of Michigan

Real-time Measurement of Epithelial Barrier Permeability in Human Intestinal Organoids

Department of Internal Medicine,
Division of Gastroenterology,
Department of Internal Medicine, Division of Gastroenterology