Jonathan Himmelfarb

Identification, Confirmation, and Replication of Novel Urinary MicroRNA Biomarkers in Lupus Nephritis and Diabetic Nephropathy.

Ironing out the pathogenesis of acute kidney injury.

Tipping the redox balance of oxidative stress in fibrogenic pathways in chronic kidney disease.

Resolved: Targeting a higher hemoglobin is associated with greater risk in patients with CKD anemia: con.

Comparison of methods for estimating glomerular filtration rate in critically ill patients with acute kidney injury.

ESRD impairs nonrenal clearance of fexofenadine but not midazolam.

Decreased pulse pressure during hemodialysis is associated with improved 6-month outcomes.

Creating research infrastructure and functionality to address chronic kidney disease: the Kidney Research Institute.

Preexisting chronic kidney disease: a potential for improved outcomes from acute kidney injury.

Acute kidney injury in the elderly: problems and prospects.

Uremic toxicity, oxidative stress, and hemodialysis as renal replacement therapy.

Mechanisms of drug-induced nephrotoxicity.

Association of major depression and mortality in Stage 5 diabetic chronic kidney disease.

Fluid accumulation, recognition and staging of acute kidney injury in critically-ill patients.

Multiple-dose pharmacokinetics and pharmacodynamics of N-acetylcysteine in patients with end-stage renal disease.

Hemodialysis.

MCP-1 gene activation marks acute kidney injury.

Effluent volume in continuous renal replacement therapy overestimates the delivered dose of dialysis.

Sepsis as a cause and consequence of acute kidney injury: Program to Improve Care in Acute Renal Disease.

Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease.

Advances in understanding ischemic acute kidney injury.

Use of aspirin associates with longer primary patency of hemodialysis grafts.

Temporal trends in the prevalence of diabetic kidney disease in the United States.

HMG-CoA reductase activation and urinary pellet cholesterol elevations in acute kidney injury.

Acute kidney injury episodes and chronic kidney disease risk in diabetes mellitus.

Regional differences in dialysis care and mortality among American Indians and Alaska Natives.

Toward the optimal dose metric in continuous renal replacement therapy.

The serum 24,25-dihydroxyvitamin D concentration, a marker of vitamin D catabolism, is reduced in chronic kidney disease.

Homelessness and CKD: a cohort study.

Assessment of physical activity in chronic kidney disease.

A prospective study of frailty in nephrology-referred patients with CKD.

Periodontitis associated with chronic kidney disease among Mexican Americans.

Acute kidney injury is associated with increased hospital mortality after stroke.

Paricalcitol does not improve glucose metabolism in patients with stage 3-4 chronic kidney disease.

The inexorable rise of AKI: can we bend the growth curve?

Dialysis in 2012: Could longer and more frequent haemodialysis improve outcomes?

Kidney disease and increased mortality risk in type 2 diabetes.

Association between physical performance and all-cause mortality in CKD.

Objectives and design of the hemodialysis fistula maturation study.

Initiation of dialysis should be timely: neither early nor late.

Adverse effects of systemic glucose absorption with peritoneal dialysis: how good is the evidence?

Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport.

New therapies for diabetic kidney disease.

Physical activity and change in estimated GFR among persons with CKD.

Characteristics and performance of minority-serving dialysis facilities.

Provision of antioxidant therapy in hemodialysis (PATH): a randomized clinical trial.

Dialysis therapies: a National Dialogue.

Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system.

Anticoagulation, delivered dose and outcomes in CRRT: The program to improve care in acute renal disease (PICARD).

Estimated GFR and Circulating 24,25-Dihydroxyvitamin D3 Concentration: A Participant-Level Analysis of 5 Cohort Studies and Clinical Trials.

Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease.

Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease.

Developing microphysiological systems for use as regulatory tools--challenges and opportunities.

Homelessness and risk of end-stage renal disease.

Omega-3 fatty acids inhibit the up-regulation of endothelial chemokines in maintenance hemodialysis patients.

A pilot randomized crossover trial assessing the safety and short-term effects of pomegranate supplementation in hemodialysis patients.

Self-rated health and adverse events in CKD.

Changes in symptom burden and physical performance with initiation of dialysis in patients with chronic kidney disease.

Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.

Evaluating risk of ESRD in the urban poor.

Creatinine clearance, walking speed, and muscle atrophy: a cohort study.

Uncorrected and Albumin-Corrected Calcium, Phosphorus, and Mortality in Patients Undergoing Maintenance Dialysis.

Predictors of treatment with dialysis modalities in observational studies for comparative effectiveness research.

A Cluster of Proteins Implicated in Kidney Disease Is Increased in High-Density Lipoprotein Isolated from Hemodialysis Subjects.

Association of plasma F2-isoprostanes and isofurans concentrations with erythropoiesis-stimulating agent resistance in maintenance hemodialysis patients.

Rapid and sensitive analysis of reduced and oxidized coenzyme Q10 in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and application to studies in healthy human subjects.

Maintenance Dialysis throughout the World in Years 1990 and 2010.

A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro.

Volume Overload: Prevalence, Risk Factors, and Functional Outcome in Survivors of Septic Shock.

Urine matrix metalloproteinase-7 and risk of kidney disease progression and mortality in type 2 diabetes.

RNA Sequencing Identifies Novel Translational Biomarkers of Kidney Fibrosis.

Border Health: State-Level Variation in Predialysis Nephrology Care.

Associations between single nucleotide polymorphisms in the FAS pathway and acute kidney injury.

Biomarkers of Endothelial Activation Are Associated with Poor Outcome in Critical Illness.

Dietary Acid Load is Associated With Serum Bicarbonate but not Insulin Sensitivity in Chronic Kidney Disease.

Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress.

Tubular Secretion in CKD.

Racial and Ethnic Disparities in Use of and Outcomes with Home Dialysis in the United States.

A Novel Three-Dimensional Human Peritubular Microvascular System.

Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism.

Association of Vascular Access Type with Mortality, Hospitalization, and Transfer to In-Center Hemodialysis in Patients Undergoing Home Hemodialysis.

Host derived biomarkers of inflammation, apoptosis, and endothelial activation are associated with clinical outcomes in patients with bacteremia and sepsis regardless of microbial etiology.

Impaired Glucose and Insulin Homeostasis in Moderate-Severe CKD.

Risk Factors for Rapid Kidney Function Decline Among African Americans: The Jackson Heart Study (JHS).

Detection of Drug-Induced Acute Kidney Injury in Humans Using Urinary KIM-1, miR-21, -200c, and -423.

Mitochondrial dysfunction and oxidative stress in patients with chronic kidney disease.

Markers of kidney disease and risk of subclinical and clinical heart failure in African Americans: the Jackson Heart Study.

Risk prediction to inform surveillance of chronic kidney disease in the US Healthcare Safety Net: a cohort study.

CKD and Muscle Mitochondrial Energetics.

Diabetes, Kidney Disease, and Cardiovascular Outcomes in the Jackson Heart Study.

Association of markers of endothelial dysregulation Ang1 and Ang2 with acute kidney injury in critically ill patients.

A wearable artificial kidney for patients with end-stage renal disease.

Vascular Function at Baseline in the Hemodialysis Fistula Maturation Study.

Decellularized Human Kidney Cortex Hydrogels Enhance Kidney Microvascular Endothelial Cell Maturation and Quiescence.

Association of FMO3 Variants and Trimethylamine N-Oxide Concentration, Disease Progression, and Mortality in CKD Patients.

Development of a microphysiological model of human kidney proximal tubule function.

Extended-hours hemodialysis is associated with lower mortality risk in patients with end-stage renal disease.

Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics.

Indication for Dialysis Initiation and Mortality in Patients With Chronic Kidney Failure: A Retrospective Cohort Study.

Storage Time and Urine Biomarker Levels in the ASSESS-AKI Study.

Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death.

Physical activity and metabolic health in chronic kidney disease: a cross-sectional study.

The CKD Classification System in the Precision Medicine Era.

Effect of Coenzyme Q on Biomarkers of Oxidative Stress and Cardiac Function in Hemodialysis Patients: The CoQ Biomarker Trial.

Absolute Rates of Heart Failure, Coronary Heart Disease, and Stroke in Chronic Kidney Disease: An Analysis of 3 Community-Based Cohort Studies.

Growth Differentiation Factor-15 and Risk of CKD Progression.

Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.

Association of Vitamin D Metabolites With Arterial Function in the Hemodialysis Fistula Maturation Study.

Global Cardiovascular and Renal Outcomes of Reduced GFR.

A Two-Biomarker Model Predicts Mortality in the Critically Ill with Sepsis.

Intimal Hyperplasia, Stenosis, and Arteriovenous Fistula Maturation Failure in the Hemodialysis Fistula Maturation Study.

Histopathology of Veins Obtained at Hemodialysis Arteriovenous Fistula Creation Surgery.

Kidney function is associated with an altered protein composition of high-density lipoprotein.

Circulating levels of soluble Fas (sCD95) are associated with risk for development of a nonresolving acute kidney injury subphenotype.

Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease.

Metabolic Effects of Diet and Exercise in Patients with Moderate to Severe CKD: A Randomized Clinical Trial.

Concise Review: Current and Emerging Biomarkers of Nephrotoxicity.

Clinical Genetic Testing for APOL1: Are we There Yet?

Acute Kidney Injury and Risk of Incident Heart Failure Among US Veterans.

Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity.

Perioperative THR-184 and AKI after Cardiac Surgery.

Weekly Standard Kt/V and Clinical Outcomes in Home and In-Center Hemodialysis.

Relationships Between Clinical Processes and Arteriovenous Fistula Cannulation and Maturation: A Multicenter Prospective Cohort Study.

A 3D Human Renal Cell Carcinoma-on-a-Chip for the Study of Tumor Angiogenesis.

High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping.

GDF-15, Galectin 3, Soluble ST2, and Risk of Mortality and Cardiovascular Events in CKD.

Bioelectrical Impedance Analysis Measures and Clinical Outcomes in CKD.

Novel PAradigm to improve Inflammatory burden in end stage Renal disease (rePAIR): study protocol for a randomized controlled trial.

Reevaluating the role of megalin in renal vitamin D homeostasis using a human cell-derived microphysiological system.

Alteration of HDL Protein Composition with Hemodialysis Initiation.

Effect of Anti-Hypertensive Medication History on Arteriovenous Fistula Maturation Outcomes.

Chronic kidney disease attenuates the plasma metabolome response to insulin.

Human Organ-Specific Endothelial Cell Heterogeneity.

Kidneys on Chips: Emerging Technology for Preclinical Drug Development.

Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip.

A prospective cohort study of acute kidney injury and kidney outcomes, cardiovascular events, and death.

Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project.

Prospective Cohort Study of Renin-Angiotensin System Blocker Usage after Hospitalized Acute Kidney Injury.

Biomarkers of inflammation and repair in kidney disease progression.

Achieved blood pressure post-acute kidney injury and risk of adverse outcomes after AKI: A prospective parallel cohort study.

Angiopoietins as Prognostic Markers for Future Kidney Disease and Heart Failure Events after Acute Kidney Injury.

A reference tissue atlas for the human kidney.

Plasma Soluble Tumor Necrosis Factor Receptor Concentrations and Clinical Events After Hospitalization: Findings From the ASSESS-AKI and ARID Studies.

Longitudinal biomarkers and kidney disease progression after acute kidney injury.

Joint Modeling of Clinical and Biomarker Data in Acute Kidney Injury Defines Unique Subphenotypes with Differing Outcomes.

Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients.

The ASSESS-AKI Study found urinary epidermal growth factor is associated with reduced risk of major adverse kidney events.

FSGS Recurrence Collaboration: Report of a Symposium.

Fistula first, catheter last: can the mouth be second?

Acute kidney injury genetic risks: taking it 1 SNP at a time.

Corrigendum to "Acute kidney injury genetic risks: taking it 1 SNP at a time." Kidney International 2024;106:188-190.

Biomarker Panels for Predicting Progression of Kidney Disease in Acute Kidney Injury Survivors.

Synthetic vascular graft that heals and regenerates.

Alternative splicing of uromodulin enhances mitochondrial metabolism for adaptation to stress in kidney epithelial cells.