Ran Zhuang

Department of Immunology, Fourth Military Medical University

Affiliated withFourth Military Medical University

Research Area

Immunology and Infection

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2022

Other Publications

Article	Year
[Cloning, prokaryotic expression of LAIR and identification of their immunological reactivities]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\| PubMed ID: 15151743	2003
[Changes and significance of TNF, sIL-2R, IL-6, IL-4 and IFN-gamma levels in plasma from the patients with hemorrhagic fever with renal syndrome]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\| PubMed ID: 15555451	2004
[Apoptosis-inducing ligand TRAIL can be recruited to lipid rafts]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\| PubMed ID: 15629071	2005
Expression pattern of epithelial cell adhesion molecule on normal and malignant colon tissues. World journal of gastroenterology\| PubMed ID: 15637741	2005
[Regulation of soluble TRAIL and membrane TRAIL in Jurkat cells by PMA]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\| PubMed ID: 15862138	2005
[Preparation, purification and identification of the rabbit antibody against extracellular region of mLAIR-1]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\| PubMed ID: 16143065	2005
Generation of monoclonal antibodies to cancer/testis (CT) antigen CT10/MAGE-C2. Cancer immunity\| PubMed ID: 16594646	2006
Dynamic changes of apoptosis-inducing ligands and Th1/Th2 like subpopulations in Hantaan virus-induced hemorrhagic fever with renal syndrome. Clinical immunology (Orlando, Fla.)\| PubMed ID: 16616877	2006
[Preparation and characterization of monoclonal antibodies against human CD112 (Nectin2/PRR2)]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\| PubMed ID: 17428395	2007
Purification of GFP fusion proteins with high purity and yield by monoclonal antibody-coupled affinity column chromatography. Protein expression and purification\| PubMed ID: 18342538	2008
Generation of monoclonal antibodies against Escherichia coli DsbA. Hybridoma (2005)\| PubMed ID: 18642678	2008
Application of sandwich ELISA for detecting tag fusion proteins in high throughput. Applied microbiology and biotechnology\| PubMed ID: 18818915	2008
Expression of CD226 antagonizes apoptotic cell death in murine thymocytes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19380793	2009
Increased levels of soluble CD226 in sera accompanied by decreased membrane CD226 expression on peripheral blood mononuclear cells from cancer patients. BMC immunology\| PubMed ID: 19490613	2009
[Study on the effect of CD4+CD25+ regulatory T cell adoptive transfusion on humoral immune function in rat composite tissue allotransplantation model]. Zhonghua wai ke za zhi [Chinese journal of surgery]\| PubMed ID: 20302759	2010
Cystatin C, a novel urinary biomarker for sensitive detection of acute kidney injury during haemorrhagic fever with renal syndrome. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals\| PubMed ID: 20450259	2010
miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1. Cancer science\| PubMed ID: 22320217	2012
Establishment of reverse direct ELISA and its application in screening high-affinity monoclonal antibodies. Hybridoma (2005)\| PubMed ID: 22894783	2012
Identification of a novel B-cell epitope of Hantaan virus glycoprotein recognized by neutralizing 3D8 monoclonal antibody. The Journal of general virology\| PubMed ID: 22933664	2012
Plexin-B1: a potential diagnostic biomarker for glioma and a future target for glioma immunotherapy. Journal of neuroimmunology\| PubMed ID: 22939532	2012
The genetic polymorphisms of HLA are strongly correlated with the disease severity after Hantaan virus infection in the Chinese Han population. Clinical & developmental immunology\| PubMed ID: 23091554	2012
Sustained high level of serum VEGF at convalescent stage contributes to the renal recovery after HTNV infection in patients with hemorrhagic fever with renal syndrome. Clinical & developmental immunology\| PubMed ID: 23097674	2012
Heterogeneous expression of CT10, CT45 and GAGE7 antigens and their prognostic significance in human breast carcinoma. Japanese journal of clinical oncology\| PubMed ID: 23315387	2013
Interleukin-17 plays a critical role in the acute rejection of intestinal transplantation. World journal of gastroenterology\| PubMed ID: 23429965	2013
HLA-A2 and B35 restricted hantaan virus nucleoprotein CD8+ T-cell epitope-specific immune response correlates with milder disease in hemorrhagic fever with renal syndrome. PLoS neglected tropical diseases\| PubMed ID: 23469304	2013
Expression of leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) on osteoclasts and its potential role in rheumatoid arthritis. Clinics (Sao Paulo, Brazil)\| PubMed ID: 23778340	2013
Elevated plasma soluble Sema4D/CD100 levels are associated with disease severity in patients of hemorrhagic fever with renal syndrome. PloS one\| PubMed ID: 24040126	2013
The role of LAIR-1 (CD305) in T cells and monocytes/macrophages in patients with rheumatoid arthritis. Cellular immunology\| PubMed ID: 24380839	2014
Hantaan virus infection induces CXCL10 expression through TLR3, RIG-I, and MDA-5 pathways correlated with the disease severity. Mediators of inflammation\| PubMed ID: 24701034	2014
Increased plasma cell-free DNA level during HTNV infection: correlation with disease severity and virus load. Viruses\| PubMed ID: 25029493	2014
UPR decreases CD226 ligand CD155 expression and sensitivity to NK cell-mediated cytotoxicity in hepatoma cells. European journal of immunology\| PubMed ID: 25209846	2014
IL-33/ST2 correlates with severity of haemorrhagic fever with renal syndrome and regulates the inflammatory response in Hantaan virus-infected endothelial cells. PLoS neglected tropical diseases\| PubMed ID: 25658420	2015
Soluble Scavenger Receptor CD163 Is Associated with Severe Acute Kidney Injury in Patients with Hantaan Virus Infection. Viral immunology\| PubMed ID: 25789628	2015
Hantaan virus infection induces both Th1 and ThGranzyme B+ cell immune responses that associated with viral control and clinical outcome in humans. PLoS pathogens\| PubMed ID: 25836633	2015
Elevated Plasma Soluble CD14 Levels Correlate with the Monocyte Response Status During Hantaan Virus Infection in Humans. Viral immunology\| PubMed ID: 26196589	2015
CD8low CD100- T Cells Identify a Novel CD8 T Cell Subset Associated with Viral Control during Human Hantaan Virus Infection. Journal of virology\| PubMed ID: 26378166	2015
COMP-Ang1 promotes long-term survival of allogeneic islet grafts in a bioinert perforated chamber by inhibiting inflammation via inhibition of the TLR4 signaling pathway. Biotechnology letters\| PubMed ID: 26875093	2016
CD226 reduces endothelial cell glucose uptake under hyperglycemic conditions with inflammation in type 2 diabetes mellitus. Oncotarget\| PubMed ID: 26910838	2016
Specially modified stromal and immune microenvironment in injected bone marrow following intrabone transplantation facilitates allogeneic hematopoietic stem cell engraftment. Experimental hematology\| PubMed ID: 27090963	2016
Structure and Function of HLA-A*02-Restricted Hantaan Virus Cytotoxic T-Cell Epitope That Mediates Effective Protective Responses in HLA-A2.1/K(b) Transgenic Mice. Frontiers in immunology\| PubMed ID: 27551282	2016
Sustained High Levels of Both Total and High Molecular Weight Adiponectin in Plasma during the Convalescent Phase of Haemorrhagic Fever with Renal Syndrome Are Associated with Disease Severi... Journal of immunology research\| PubMed ID: 28424792	2017
Elevated Plasma Growth Arrest-Specific 6 Protein Levels Are Associated with the Severity of Disease During Hantaan Virus Infection in Humans. Viral immunology\| PubMed ID: 28537534	2017
Novel Identified HLA-A*0201-Restricted Hantaan Virus Glycoprotein Cytotoxic T-Cell Epitopes Could Effectively Induce Protective Responses in HLA-A2.1/K Transgenic Mice May Associate with the... Frontiers in immunology\| PubMed ID: 29312318	2017
Blocking CD226 Promotes Allogeneic Transplant Immune Tolerance and Improves Skin Graft Survival by Increasing the Frequency of Regulatory T Cells in a Murine Model. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 29550821	2018
Effects of CD100 promote wound healing in diabetic mice. Journal of molecular histology\| PubMed ID: 29637382	2018
ADAR1 attenuates allogeneic graft rejection by suppressing miR-21 biogenesis in macrophages and promoting M2 polarization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 29694248	2018
TIGIT-Fc alleviates acute graft-versus-host disease by suppressing CTL activation via promoting the generation of immunoregulatory dendritic cells. Biochimica et biophysica acta. Molecular basis of disease\| PubMed ID: 29960041	2018
Silencing LAIR-1 in human THP-1 macrophage increases foam cell formation by modulating PPARγ and M2 polarization. Cytokine\| PubMed ID: 30176557	2018
CD226 is involved in megakaryocyte activation and early-stage differentiation. Molecular immunology\| PubMed ID: 30738249	2019
[CD226 knockout aggravates radiation-induced liver injury in mice]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\| PubMed ID: 30914115	2019
CD226 deficiency on regulatory T cells aggravates renal fibrosis via up-regulation of Th2 cytokines through miR-340. Journal of leukocyte biology\| PubMed ID: 31802539	2020
ECDI-fixed donor splenocytes prolong skin allograft survival by promoting M2 macrophage polarization and inducing regulatory T cells. FASEB bioAdvances\| PubMed ID: 32123816	2019
Deficiency of platelet adhesion molecule CD226 causes megakaryocyte development and platelet hyperactivity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 32248623	2020
ADAR1 Alleviates Inflammation in a Murine Sepsis Model via the ADAR1-miR-30a-SOCS3 Axis. Mediators of inflammation\| PubMed ID: 32273831	2020
[The conditional knockout of CD226 gene reduces acute lung injury in mice with hemorrhagic shock]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\| PubMed ID: 32314710	2020
[Exploration and practice of online teaching system of medical immunology based on small private online course (SPOC) model during coronavirus disease 2019 (COVID-19) pandemic]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\| PubMed ID: 32519674	2020
LAIR-1 overexpression inhibits epithelial-mesenchymal transition in osteosarcoma via GLUT1-related energy metabolism. World journal of surgical oncology\| PubMed ID: 32563267	2020
Protective CD8 T-cell response against Hantaan virus infection induced by immunization with designed linear multi-epitope peptides in HLA-A2.1/K transgenic mice. Virology journal\| PubMed ID: 33028368	2020
[Preparation and application of mouse-derived monoclonal antibodies against mouse CD226]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\| PubMed ID: 33148389	2020
Splenectomy improves liver fibrosis via tumor necrosis factor superfamily 14 (LIGHT) through the JNK/TGF-β1 signaling pathway. Experimental & molecular medicine\| PubMed ID: 33654222	2021
Silencing of HuR Inhibits Osteosarcoma Cell Epithelial-Mesenchymal Transition AGO2 in Association With Long Non-Coding RNA XIST. Frontiers in oncology\| PubMed ID: 33816232	2021
Adiponectin's globular domain inhibits T cell activation by interacting with LAIR-1. Biochemical and biophysical research communications\| PubMed ID: 34403808	2021
Elevated Plasma Fractalkine Level Is Associated with the Severity of Hemorrhagic Fever with Renal Syndrome in Humans. Viral immunology\| PubMed ID: 34463135	2021
GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma. Journal for immunotherapy of cancer\| PubMed ID: 34489334	2021
CD226 Is Required to Maintain Megakaryocytes/Platelets Homeostasis in the Treatment of Knee Osteoarthritis With Platelet-Rich Plasma in Mice. Frontiers in pharmacology\| PubMed ID: 34526904	2021
Platelet-mediated tumor metastasis mechanism and the role of cell adhesion molecules. Critical reviews in oncology/hematology\| PubMed ID: 34662726	2021
CD226 deficiency promotes glutaminolysis and alleviates mitochondria damage in vascular endothelial cells under hemorrhagic shock. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 34669985	2021
Acute Cold Water-Immersion Restraint Stress Induces Intestinal Injury and Reduces the Diversity of Gut Microbiota in Mice. Frontiers in cellular and infection microbiology\| PubMed ID: 34722327	2021
[Preparation and identification of mouse-derived monoclonal antibodies to human ST2 molecule]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\| PubMed ID: 34809742	2021
CD226 knockout alleviates high-fat diet induced obesity by suppressing proinflammatory macrophage phenotype. Journal of translational medicine\| PubMed ID: 34823548	2021
Interleukin-6 absence triggers intestinal microbiota dysbiosis and mucosal immunity in mice. Cytokine\| PubMed ID: 35276634	2022