Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model

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2.2K Views

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09:02 min

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September 27th, 2024

DOI :

10.3791/66986-v

September 27th, 2024

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Bryan D. Kim¹^,², Sujan K. Mondal¹^,³, Elizabeth Kenyon¹^,³, Ming Chen¹^,³, Christiane L. Mallett³^,⁴, Ana C. deCarvalho⁵, Zdravka Medarova⁶, Anna Moore¹^,³

¹Precision Health Program, Michigan State University, ²Department of Biomedical Engineering, College of Engineering, Michigan State University, ³Department of Radiology, College of Human Medicine, Michigan State University, ⁴Institute for Quantitative Health Science and Engineering, Michigan State University, ⁵Henry Ford Health, ⁶Transcode Therapeutics Inc.

Podsumowanie

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Nanoparticle Delivery

Glioblastoma Multiforme

Blood brain Barrier

Therapeutic Oligonucleotide

Iron Oxide Nanoparticles

Precision Medicine

Image guided Therapy

Magnetic Resonance Imaging

Molecular Heterogeneity

Crosslinked Dextran coated Nanoparticles

Rozdziały w tym wideo

0:00

Introduction

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2:26

In Vivo and Ex Vivo Imaging for Nanoparticle Tracking in Murine Glioblastoma Models