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Behavior

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A Complex Diving-For-Food Task to Investigate Social Organization and Interactions in Rats

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3.9K Views

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10:29 min

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May 8th, 2021

DOI :

10.3791/61763-v

May 8th, 2021

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Benjamin F. Gruenbaum*¹, Dmitry Frank*², Shiri Savir², Honore N. Shiyntum³, Ruslan Kuts², Max Vinokur², Israel Melamed⁴, Michael Dubilet², Alexander Zlotnik², Matthew Boyko²

¹Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, ²Division of Anesthesiology and Critical Care, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, ³Department of Biophysics and Biochemistry, Oles Honchar Dnipro National University, ⁴Department of Neurosurgery, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev

Podsumowanie

This protocol describes a method of examining social hierarchy in a rat model. Rats perform a complex diving-for-food task in which they form a distinct hierarchy according to their willingness to dive underwater and swim to obtain a food pellet. This method is used to understand decision making and social relationships among highly social animals in small groups.

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Social Hierarchy

Diving For Food Task

Decision making

Social Relationships

Sprague Dawley Rats

Experimental Groups

Depression Induction

Antidepressant Treatment

Chronic Unpredictable Stress

Food Deprivation

Water Deprivation

Environmental Stressors

Rat Behavior Experiment

Rozdziały w tym wideo

0:00

Introduction

0:43

Preparing Rats for the Experimental Procedure

2:14

Induction of Depression in Rats

3:16

Anti-depression Therapy

3:58

The Social Organization Test (Complex Diving-for-Food Task)

5:19

Performing Diving-for-Food Task

6:03

Assessment of Depressive-like Behavior: The Sucrose Preference Test

7:14

Representative Results

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