Center for Cancer Pharmacology,
Center for Excellence in Environmental Toxicology
Clementina Mesaros has not added Biography.
If you are Clementina Mesaros and would like to personalize this page please email our Author Liaison for assistance.
Iso[7]LGD2-protein adducts are abundant in vivo and free radical-induced oxidation of an arachidonyl phospholipid generates this D series isolevuglandin in vitro.
Chemical research in toxicology May, 2004 | Pubmed ID: 15144218
Identification of oxidatively truncated ethanolamine phospholipids in retina and their generation from polyunsaturated phosphatidylethanolamines.
Chemical research in toxicology Feb, 2006 | Pubmed ID: 16485902
A novel 4-oxo-2(E)-nonenal-derived endogenous thiadiazabicyclo glutathione adduct formed during cellular oxidative stress.
Chemical research in toxicology Jul, 2007 | Pubmed ID: 17550273
Targeted quantitative analysis of eicosanoid lipids in biological samples using liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Sep, 2009 | Pubmed ID: 19345647
Secondhand smoke inhibits both Cl- and K+ conductances in normal human bronchial epithelial cells.
Respiratory research , 2009 | Pubmed ID: 19943936
A 13-Oxo-9,10-epoxytridecenoate phospholipid analogue of the genotoxic 4,5-epoxy-2E-decenal: detection in vivo, chemical synthesis, and adduction with DNA.
Chemical research in toxicology Mar, 2010 | Pubmed ID: 20131875
20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice.
PloS one , 2010 | Pubmed ID: 20422032
Analysis of epoxyeicosatrienoic acids by chiral liquid chromatography/electron capture atmospheric pressure chemical ionization mass spectrometry using [13C]-analog internal standards.
Rapid communications in mass spectrometry : RCM Nov, 2010 | Pubmed ID: 20972997
A new liquid chromatography/mass spectrometry method for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine.
Rapid communications in mass spectrometry : RCM Jan, 2011 | Pubmed ID: 21154658
Prediction of postoperative recurrence-free survival in non-small cell lung cancer by using an internationally validated gene expression model.
Clinical cancer research : an official journal of the American Association for Cancer Research May, 2011 | Pubmed ID: 21242119
Stable isotope labeling by essential nutrients in cell culture for preparation of labeled coenzyme A and its thioesters.
Analytical chemistry Feb, 2011 | Pubmed ID: 21268609
CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET).
The Journal of biological chemistry May, 2011 | Pubmed ID: 21402692
Nicotine exposure and metabolizer phenotypes from analysis of urinary nicotine and its 15 metabolites by LC-MS.
Bioanalysis Apr, 2011 | Pubmed ID: 21452992
Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.
The Biochemical journal Jul, 2011 | Pubmed ID: 21521174
8-Oxo-2'-deoxyguanosine as a biomarker of tobacco-smoking-induced oxidative stress.
Free radical biology & medicine Aug, 2012 | Pubmed ID: 22613262
Effects of 21 days of varenicline versus placebo on smoking behaviors and urges among non-treatment seeking smokers.
Journal of psychopharmacology (Oxford, England) Oct, 2012 | Pubmed ID: 22695488
Antioxidant protection by PECAM-targeted delivery of a novel NADPH-oxidase inhibitor to the endothelium in vitro and in vivo.
Journal of controlled release : official journal of the Controlled Release Society Oct, 2012 | Pubmed ID: 22974832
The effect of menthol on cigarette smoking behaviors, biomarkers and subjective responses.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Mar, 2013 | Pubmed ID: 23334588
A novel nontoxic inhibitor of the activation of NADPH oxidase reduces reactive oxygen species production in mouse lung.
The Journal of pharmacology and experimental therapeutics May, 2013 | Pubmed ID: 23475902
Bisphenol a exposure disrupts genomic imprinting in the mouse.
PLoS genetics Apr, 2013 | Pubmed ID: 23593014
Dietary Flaxseed in Non-Small Cell Lung Cancer Patients Receiving Chemoradiation.
Journal of pulmonary & respiratory medicine Aug, 2013 | Pubmed ID: 24575360
Metabolism of a representative oxygenated polycyclic aromatic hydrocarbon (PAH) phenanthrene-9,10-quinone in human hepatoma (HepG2) cells.
Chemical research in toxicology May, 2014 | Pubmed ID: 24646012
Targeted chiral analysis of bioactive arachidonic Acid metabolites using liquid-chromatography-mass spectrometry.
Metabolites , 2012 | Pubmed ID: 24957514
Inhibition of neuronal cell mitochondrial complex I with rotenone increases lipid β-oxidation, supporting acetyl-coenzyme A levels.
The Journal of biological chemistry Sep, 2014 | Pubmed ID: 25122772
Analysis of estrogens and androgens in postmenopausal serum and plasma by liquid chromatography-mass spectrometry.
Steroids Jul, 2015 | Pubmed ID: 25150018
Metabolism of propionic acid to a novel acyl-coenzyme A thioester by mammalian cell lines and platelets.
Journal of lipid research Jan, 2015 | Pubmed ID: 25424005
What are the main considerations for bioanalysis of estrogens and androgens in plasma and serum samples from postmenopausal women?
Bioanalysis , 2014 | Pubmed ID: 25529875
Ultrasensitive quantification of serum estrogens in postmenopausal women and older men by liquid chromatography-tandem mass spectrometry.
Steroids Apr, 2015 | Pubmed ID: 25637677
Rotenone Stereospecifically Increases (S)-2-Hydroxyglutarate in SH-SY5Y Neuronal Cells.
Chemical research in toxicology May, 2015 | Pubmed ID: 25800467
Estrogens and Their Genotoxic Metabolites Are Increased in Obese Prepubertal Girls.
The Journal of clinical endocrinology and metabolism Jun, 2015 | Pubmed ID: 25856214
Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes.
Biochemical pharmacology Aug, 2015 | Pubmed ID: 26032638
Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure.
Bioanalysis , 2015 | Pubmed ID: 26039812
Oncology bioanalysis: from biomarkers to drug discovery.
Biomarkers in medicine , 2015 | Pubmed ID: 26329020
Translational metabolomics in cancer research.
Biomarkers in medicine , 2015 | Pubmed ID: 26329905
Serum apolipoprotein A-1 quantification by LC-MS with a SILAC internal standard reveals reduced levels in smokers.
Bioanalysis , 2015 | Pubmed ID: 26394123
Metabolism of an Alkylated Polycyclic Aromatic Hydrocarbon 5-Methylchrysene in Human Hepatoma (HepG2) Cells.
Chemical research in toxicology Oct, 2015 | Pubmed ID: 26395544
Bacterial exploitation of phosphorylcholine mimicry suppresses inflammation to promote airway infection.
The Journal of clinical investigation Oct, 2015 | Pubmed ID: 26426079
Ultra-high sensitivity analysis of estrogens for special populations in serum and plasma by liquid chromatography-mass spectrometry: Assay considerations and suggested practices.
The Journal of steroid biochemistry and molecular biology Jan, 2016 | Pubmed ID: 26767303
Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure.
Circulation Feb, 2016 | Pubmed ID: 26819374
Andrew J. Worth*,1,2,
Dylan M. Marchione*,2,3,
Robert C. Parry1,2,
Qingqing Wang2,3,
Kevin P. Gillespie2,3,
Noelle N. Saillant4,
Carrie Sims4,
Clementina Mesaros1,2,
Nathaniel W. Snyder5,
Ian A. Blair1,2
1Center for Cancer Pharmacology, University of Pennsylvania,
2Center for Excellence in Environmental Toxicology, University of Pennsylvania,
3Penn SRP and Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania,
4Division of Traumatology, Department of Surgery, Critical Care and Acute Care Surgery, University of Pennsylvania,
5A.J. Drexel Autism Institute, Drexel University
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved