Department of Surgery,
Board of Governors Regenerative Medicine Institute,
Orthopaedic Stem Cell Research Laboratory,
Department of Biomedical Sciences,
Department of Orthopedics
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Gene-modified adult stem cells regenerate vertebral bone defect in a rat model.
Molecular pharmaceutics Oct, 2011 | Pubmed ID: 21834548
Oxygenated environment enhances both stem cell survival and osteogenic differentiation.
Tissue engineering. Part A Mar, 2013 | Pubmed ID: 23215901
Nucleus pulposus degeneration alters properties of resident progenitor cells.
The spine journal : official journal of the North American Spine Society Jul, 2013 | Pubmed ID: 23578990
Transient overexpression of Pparγ2 and C/ebpα in mesenchymal stem cells induces brown adipose tissue formation.
Regenerative medicine May, 2013 | Pubmed ID: 23627824
Real-time bioluminescence functional imaging for monitoring tissue formation and regeneration.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23929106
PTH promotes allograft integration in a calvarial bone defect.
Molecular pharmaceutics Dec, 2013 | Pubmed ID: 24131143
PTH induces systemically administered mesenchymal stem cells to migrate to and regenerate spine injuries.
Molecular therapy : the journal of the American Society of Gene Therapy Nov, 2015 | Pubmed ID: 26585691
Multiparameter evaluation of in vivo gene delivery using ultrasound-guided, microbubble-enhanced sonoporation.
Journal of controlled release : official journal of the Controlled Release Society Dec, 2015 | Pubmed ID: 26682505
BMP6-Engineered MSCs Induce Vertebral Bone Repair in a Pig Model: A Pilot Study.
Stem cells international , 2016 | Pubmed ID: 26770211
Controlling Arteriogenesis and Mast Cells Are Central to Bioengineering Solutions for Critical Bone Defect Repair Using Allografts.
Bioengineering (Basel, Switzerland) Mar, 2016 | Pubmed ID: 27141513
Human Induced Pluripotent Stem Cells Differentiate Into Functional Mesenchymal Stem Cells and Repair Bone Defects.
Stem cells translational medicine Nov, 2016 | Pubmed ID: 27400789
Quantitative chemical exchange saturation transfer MRI of intervertebral disc in a porcine model.
Magnetic resonance in medicine Dec, 2016 | Pubmed ID: 27670140
Teriparatide attenuates scarring around murine cranial bone allograft via modulation of angiogenesis.
Bone Apr, 2017 | Pubmed ID: 28119180
Systemic administration of mesenchymal stem cells combined with parathyroid hormone therapy synergistically regenerates multiple rib fractures.
Stem cell research & therapy Mar, 2017 | Pubmed ID: 28279202
In situ bone tissue engineering via ultrasound-mediated gene delivery to endogenous progenitor cells in mini-pigs.
Science translational medicine May, 2017 | Pubmed ID: 28515335
Anti-Inflammatory Peptide Attenuates Edema and Promotes BMP-2-Induced Bone Formation in Spine Fusion.
Tissue engineering. Part A Nov, 2018 | Pubmed ID: 29766758
Ultrasound-Mediated Gene Delivery Enhances Tendon Allograft Integration in Mini-Pig Ligament Reconstruction.
Molecular therapy : the journal of the American Society of Gene Therapy Jul, 2018 | Pubmed ID: 29784586
Molecular pain markers correlate with pH-sensitive MRI signal in a pig model of disc degeneration.
Scientific reports Nov, 2018 | Pubmed ID: 30478330
In Vivo Imaging of Exogenous Progenitor Cells in Tendon Regeneration via Superparamagnetic Iron Oxide Particles.
The American journal of sports medicine Sep, 2019 | Pubmed ID: 31336056
Human iPSCs can be differentiated into notochordal cells that reduce intervertebral disc degeneration in a porcine model.
Theranostics , 2019 | Pubmed ID: 31695783
The effect of insulin dependent diabetes on bone metabolism and growth after spinal fusion.
The spine journal : official journal of the North American Spine Society May, 2020 | Pubmed ID: 31759133
Omega-3 Fatty Acid Supplementation Reduces Intervertebral Disc Degeneration.
Medical science monitor : international medical journal of experimental and clinical research Dec, 2019 | Pubmed ID: 31836696
Bone-chip system to monitor osteogenic differentiation using optical imaging.
Microfluidics and nanofluidics Aug, 2019 | Pubmed ID: 32296299
NF-κB inhibitor, NEMO-binding domain peptide attenuates intervertebral disc degeneration.
The spine journal : official journal of the North American Spine Society Sep, 2020 | Pubmed ID: 32413485
Optimization of a rat lumbar IVD degeneration model for low back pain.
JOR spine Jun, 2020 | Pubmed ID: 32613167
Electrospun, synthetic bone void filler promotes human MSC function and BMP-2 mediated spinal fusion.
Journal of biomaterials applications , 2020 | Pubmed ID: 32627633
A Translational Porcine Model for Human Cell-Based Therapies in the Treatment of Posttraumatic Osteoarthritis After Anterior Cruciate Ligament Injury.
The American journal of sports medicine Oct, 2020 | Pubmed ID: 32924528
Assessing the Resident Progenitor Cell Population and the Vascularity of the Adult Human Meniscus.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association Jan, 2021 | Pubmed ID: 32979500
Advanced Glycation End Product Inhibitor Pyridoxamine Attenuates IVD Degeneration in Type 2 Diabetic Rats.
International journal of molecular sciences Dec, 2020 | Pubmed ID: 33352698
Neural crest-derived mesenchymal progenitor cells enhance cranial allograft integration.
Stem cells translational medicine May, 2021 | Pubmed ID: 33512772
Single-cell atlas unveils cellular heterogeneity and novel markers in human neonatal and adult intervertebral discs.
iScience Jul, 2022 | Pubmed ID: 35754733
Directing iPSC differentiation into iTenocytes using combined scleraxis overexpression and cyclic loading.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Jun, 2023 | Pubmed ID: 36203346
iPSC-neural crest derived cells embedded in 3D printable bio-ink promote cranial bone defect repair.
Scientific reports Nov, 2022 | Pubmed ID: 36333414
iPSC-derived tenocytes seeded on microgrooved 3D printed scaffolds for Achilles tendon regeneration.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Oct, 2023 | Pubmed ID: 36961351
Harmonization and standardization of nucleus pulposus cell extraction and culture methods.
JOR spine Mar, 2023 | Pubmed ID: 36994456
Biologically-coupled bisphosphonate chaperones effectively deliver molecules to the site of soft tissue-bone healing.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Oct, 2023 | Pubmed ID: 37087676
Single Cell Transcriptomics-Informed Induced Pluripotent Stem Cells Differentiation to Tenogenic Lineage.
bioRxiv : the preprint server for biology Jun, 2023 | Pubmed ID: 37090543
Retention of Human iPSC-Derived or Primary Cells Following Xenotransplantation into Rat Immune-Privileged Sites.
Bioengineering (Basel, Switzerland) Sep, 2023 | Pubmed ID: 37760151
Intervertebral disc human nucleus pulposus cells associated with back pain trigger neurite outgrowth in vitro and pain behaviors in rats.
Science translational medicine Dec, 2023 | Pubmed ID: 38055799
1Orthopaedic Stem Cell Research Laboratory, Cedars-Sinai Medical Center,
2Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center,
3Department of Biomedical Sciences, Cedars-Sinai Medical Center,
4Department of Orthopedics, Cedars-Sinai Medical Center,
5Department of Surgery, Cedars-Sinai Medical Center
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