biology

Biology

JoVE Core series brings biology to life through over 300 concise and easy-to-understand animated video lessons that explain key concepts in biology, plus more than 150 scientist-in-action videos that show actual research experiments conducted in today’s laboratories.

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cell biology

Cell Biology

JoVE Core Cell Biology illustrates complex cellular processes in easy-to-understand yet comprehensive animated video lessons. This collection focuses on the essential components and functions of cells, including organelles and membranes, cellular transport, and cell energetics. It is complemented by scientist-in-action videos that demonstrate the application of cell biology in real-world research experiments.

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molecular biology

Molecular Biology

JoVE Core Molecular Biology showcases the molecular processes of the cell through clear and concise animated video lessons. Additionally, in scientist-in-action videos, these concepts' application is demonstrated through real experiments in modern laboratories.

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chemistry

Chemistry

JoVE Core Chemistry brings general chemistry concepts to life using concise and easy-to-understand animated video lessons. Plus, in the scientist-in-action videos, we demonstrate classical and original research experiments performed in today's laboratories worldwide.

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organic chemistry

Organic Chemistry

JoVE Core Organic Chemistry explains basic concepts of stereochemistry, reactions, and mechanisms using concise and easy-to-understand animated video lessons. Additionally, the scientist-in-action videos demonstrate the application of related concepts in classical and original research experiments performed in today's laboratories worldwide.

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analytical chemistry

Analytical Chemistry

JoVE Core Analytical Chemistry simplifies complex chemical principles by breaking them down into clear, engaging animations, making topics from SI Units to NMR spectroscopy more accessible and straightforward. Additionally, the scientist-in-action videos highlight the application of these concepts in real-world research conducted in laboratories globally.

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physics

Physics

JoVE Core Physics introduces the theory and application of fundamental physics topics, including kinematics, dynamics, fluid mechanics, statics, waves, and acoustics, with concise and easy-to-understand animated videos. Additionally, the scientist-in-action videos demonstrate the application of related concepts in classical and original research experiments performed in today's laboratories worldwide.

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statistics

Statistics

JoVE Core Statistics introduces the concepts and application of the collection, analysis, presentation, and interpretation of data to students. These animated lessons provide an understanding of statistics beneficial to students from a wide range of disciplines. Additionally, the scientist-in-action videos demonstrate the application of related concepts in classical and original research experiments performed in today's laboratories worldwide

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anatomy and physiology

Anatomy and Physiology

JoVE Core Anatomy and Physiology showcases the anatomical and physiological details of the human body in comprehensive, clear, and engaging video animations. This collection of lessons focuses on the structures, components, functions, and requirements of the human body. It is complemented by scientist-in-action videos that demonstrate the application of this knowledge in real-world medical and research settings.

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pharmacology

JoVE Core Pharmacology provides engaging animations that explain fundamental concepts, including drug effects, classification, and pharmacokinetics. Scientist-in-action videos illustrate real-world research conducted in today's laboratories.

Pharmacology

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pharmacokinetics and pharmacodynamics

Jove Core Pharmacokinetics and Pharmacodynamics is a comprehensive collection designed to equip students with a solid understanding of the relationship between pharmacokinetics (PK) and pharmacodynamics (PD). This foundational series covers essential topics, including biopharmaceutics, drug behavior modeling, and the correlation between drug concentration and therapeutic response. It is complemented by scientist-in-action videos to demonstrate the real-world application.

Pharmacokinetics and Pharmacodynamics

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nursing

JoVE Core Nursing offers concise animated lessons on nursing practices, covering health systems, nursing organizations, and health concepts. It includes practical communication, infection prevention, and nursing fundamentals, providing students with a clear understanding of nursing principles.

Nursing

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introduction to psychology

JoVE Core Introduction to Psychology offers an engaging learning experience on the fundamental principles of psychology through concise video lessons. Students will explore important topics such as cognitive processes, emotional regulation, and neural mechanisms, establishing a strong foundation in the study of the mind and human behavior. This series provides an accessible and captivating approach to grasp the essential concepts of the discipline.

Introduction to Psychology

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social psychology

Social Psychology

JoVE Core Social Psychology brings the foundations of our social world to life. Through 66 concise and easy-to-understand animated video lessons, we explain key concepts in the field. Plus, in another 25 scientist-in-action videos, we demonstrate classical and original research experiments performed in the laboratory.

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electrical engineering

JoVE Core Electrical Engineering offers easy-to-understand animated videos that cover fundamental concepts of electric circuits along with circuit analysis techniques. It incorporates first-order and second-order circuits using operational amplifiers and circuit transformation concepts. The inclusion of practical design examples and real-world applications through scientist-in-action videos adds significant educational value, making complex concepts accessible.

Electrical Engineering

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mechanical engineering

JoVE Core Mechanical Engineering offers concise, easy-to-understand animated videos covering key topics such as equilibrium, forces, truss analysis, and structural mechanics. Explore their real-world applications, and witness these concepts in action through scientist-led experiments.


Mechanical Engineering

JoVE Core Mechanical Engineering offers concise, easy-to-understand animated videos covering key topics such as equilibrium, forces, truss analysis, and structural mechanics. Explore their real-world applications, and witness these concepts in action through scientist-led experiments.

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civil engineering

JoVE Core Civil Engineering offers a foundational exploration of essential construction materials such as bricks, stones, steel, wood, and concrete, along with fluid mechanics topics like flow over immersed bodies, open channel flow, and dimensional modeling. It also covers key surveying concepts, including leveling, traverse adjustments, curve design, topographic mapping, and geospatial technologies (GPS & GIS). Science-in-action videos showcase laboratory research on materials, fluids, and surveying practices in real-world engineering systems.

Civil Engineering

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microbiology

JoVE Core Microbiology provides an engaging introduction to the microbial world and its influence on health, industry, and the environment. This comprehensive collection covers key concepts such as microbial structure, metabolism, genetics, and ecology. It introduces essential laboratory techniques and microscopy methods through visually engaging animations. Corresponding scientist-in-action videos bridge classroom concepts with real-world research and applications.

Microbiology

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medical-surgical nursing

JoVE Core Medical-Surgical Nursing offers comprehensive animated lessons that cover major systems of the human body, integrating anatomy and physiology with system-specific assessments. This collection encompasses disease conditions based on the body systems, detailing their pathophysiology, medical and surgical management, and nursing interventions. These lessons provide a clear and practical understanding of medical-surgical care, equipping students with essential skills for managing patient care in various clinical settings.

Medical-Surgical Nursing

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jove core

JoVE Core

Video textbooks which explain concepts taught in undergraduate courses through high-impact animations and real-life experiments.

Education

unit 1

Unit 1

key terms and concepts

KEY TERMS AND CONCEPTS

scientists in action

SCIENTISTS IN ACTION

pharmacokinetics: drug distribution and protein binding

Pharmacokinetics: Drug Distribution and Protein Binding

Chapter 4 drug distribution: overview

Drug Distribution: Overview

Distribution refers to the two-way movement of a drug between different compartments within the body.
It is a passive process driven by the concentration ...

factors affecting drug distribution: tissue permeability

factors-affecting-drug-distribution-tissue-permeability

Factors Affecting Drug Distribution: Tissue Permeability

Drug distribution across biological membranes to target tissues relies on the drug&#39;s physicochemical properties, such as molecular size, ionization ...

factors affecting drug distribution: physiological barriers

factors-affecting-drug-distribution-physiological-barriers

Factors Affecting Drug Distribution: Physiological Barriers

Drug distribution is governed by several physiological barriers.
The simple capillary endothelial barrier limits the passage of drugs larger than 600 ...

factors affecting drug distribution: organ perfusion rate

factors-affecting-drug-distribution-organ-perfusion-rate

Factors Affecting Drug Distribution: Organ Perfusion Rate

Drug distribution can be perfusion rate-limited, particularly when the drug is highly lipophilic, and the membrane to cross is highly permeable.
The ...

factors affecting drug distribution: miscellaneous factors

factors-affecting-drug-distribution-miscellaneous-factors

Factors Affecting Drug Distribution: Miscellaneous Factors

Drug distribution can be affected by various factors.
It can vary with age due to differences in body composition. For instance, older adults have less ...

volume of distribution

Volume of Distribution

The apparent volume of distribution or Vd is a key pharmacokinetic parameter signifying the hypothetical body fluid volume into which a drug disperses.
It ...

protein-drug binding: mechanism and kinetics

protein-drug-binding-mechanism-and-kinetics

Protein-Drug Binding: Mechanism and Kinetics

Protein-drug binding is the interaction between drugs and proteins in the body.
It can be either intracellular binding, which involves drug interactions ...

drug binding to blood components

Drug Binding to Blood Components

When drugs enter the systemic circulation, they interact with blood components like human serum albumin or HSA, &#945;1-acid glycoprotein or AAG, ...

tissue-drug binding: localization of drugs and its significance

tissue-drug-binding-localization-of-drugs-and-its-significance

Tissue-Drug Binding: Localization of Drugs and its Significance

Body tissues comprise 40-90% of body weight depending on body composition. They can serve as drug storage sites, competing with plasma binding sites.
...

protein-drug binding: determination methods

protein-drug-binding-determination-methods

Protein-Drug Binding: Determination Methods

Protein-drug binding is determined through indirect and direct methods.
Indirect methods involve isolating the bound drug from its free form in biological ...

factors affecting protein-drug binding: drug-related factors

factors-affecting-protein-drug-binding-drug-related-factors

Factors Affecting Protein-Drug Binding: Drug-Related Factors

Protein-drug binding can be affected by various drug-related factors.
The degree of protein binding is closely related to a drug&#39;s lipophilicity, with ...

factors affecting protein-drug binding: protein-related factors

factors-affecting-protein-drug-binding-protein-related-factors

Factors Affecting Protein-Drug Binding: Protein-Related Factors

Drug binding to proteins depends on various factors, including physicochemical properties, protein concentration, disease states, and the number of ...

factors affecting protein-drug binding: drug interactions

factors-affecting-protein-drug-binding-drug-interactions

Factors Affecting Protein-Drug Binding: Drug Interactions

Drug displacement interactions arise when drugs compete for the same binding site, leading to displacement.
The extent of displacement depends on the ...

factors affecting protein-drug binding: patient-related factors

factors-affecting-protein-drug-binding-patient-related-factors

Factors Affecting Protein-Drug Binding: Patient-Related Factors

Protein-drug binding varies with many patient-related factors.
Age impacts binding due to varying protein content in different age groups. Neonates ...

visualizing and quantifying pharmaceutical compounds within skin using coherent raman scattering imaging

visualizing-quantifying-pharmaceutical-compounds-within-skin-using

Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging

Cutaneous pharmacokinetics (cPK) after topical formulation application has been a research area of particular interest for regulatory and drug development ...

host cell protein analysis using enrichment beads coupled with limited digestion

host-cell-protein-analysis-using-enrichment-beads-coupled-with

Host Cell Protein Analysis using Enrichment Beads Coupled with Limited Digestion

Host cell proteins (HCPs) are impurities that can adversely affect therapeutic proteins, even in small quantities. To evaluate the potential risks ...

reconstruction of the blood-brain barrier <em>in vitro</em> to model and therapeutically target neurological disease

reconstruction-blood-brain-barrier-vitro-to-model-therapeutically

Reconstruction of the Blood-Brain Barrier <em>In Vitro</em> to Model and Therapeutically Target Neurological Disease

The blood-brain barrier (BBB) is a key physiological component of the central nervous system (CNS), maintaining nutrients, clearing waste, and protecting ...

Core - Pharmacokinetics and Pharmacodynamics

Pharmacokinetics: Drug Distribution and Protein Binding