Entrar

Korea National University of Science and Technology (UST)

1 ARTICLES PUBLISHED IN JoVE

Bioengineering

High-Throughput Bioprinting Method for Modeling Vascular Permeability in Standard Six-well Plates with Size and Pattern Flexibility

Ashfaq Ahmad^1,2, Mst Zobaida Akter^1,2, Seo-Yeon Kim^1,2, Yeong-Jin Choi^3,4, Hee-Gyeong Yi^1,2

¹Department of Convergence Biosystems Engineering, College of Agriculture and Life Sciences (CALS), Chonnam National University, ²Interdisciplinary Program in IT-Bio Convergence System, Chonnam National University, ³Advanced Bio and Healthcare Materials Research Division, Korea Institute of Materials Science (KIMS), ⁴Advanced Materials Engineering, Korea National University of Science and Technology (UST)

We present a protocol for high-throughput production of vascular channels with flexible sizes and desired patterns on a standard six-well plate using 3D bioprinting technology, referred to as vessels-on-a-plate (VOP). This platform has the potential to advance the development of therapeutics for the disorders associated with compromised endothelium.