Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

1 ARTICLES PUBLISHED IN JoVE

Bioengineering

Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications

Goutam Pramanik¹, Alena Keprova¹, Jan Valenta², Vaclav Bocan³, Klaudia Kvaková^1,4, Lenka Libusova³, Petr Cigler¹

¹Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, ²Department of Chemical Physics and Optics, Faculty of Mathematics and Physics, Charles University, ³Department of Cell Biology, Faculty of Science, Charles University, ⁴First Faculty of Medicine, Charles University

A reliable and easily reproducible method for preparation of functionalizable, near-infrared emitting photoluminescent gold nanoclusters and their direct detection inside HeLa cells by flow cytometry and confocal laser scanning microscopy is described.