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Ludwig-Maximilians-University

1 ARTICLES PUBLISHED IN JoVE

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Medicine

Real-Time Electrocardiogram Monitoring During Treadmill Training in Mice
Philipp Tomsits *1,2,4, Aparna Sharma Chivukula *1,2, Kavi Raj Chataut *1,2, Agus Simahendra 3, Ludwig T. Weckbach 1,2,3, Stefan Brunner 1, Sebastian Clauss 1,2,4
1Department of Medicine I, University Hospital Munich, Ludwig-Maximilians University Munich (LMU), 2DZHK (German Centre for Cardiovascular Research), Partner Site Munich, Munich Heart Alliance (MHA), 3Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University, 4Institute of Surgical Research at the Walter-Brendel-Centre of Experimental Medicine, University Hospital Munich, Ludwig-Maximilians University Munich (LMU)

Electrocardiogram (ECG) is the key variable to understanding cardiac electrophysiology. Physical exercise has beneficial effects but may also be harmful in the context of cardiovascular diseases. This manuscript provides a method of recording real-time ECG during exercise, which can serve to investigate its effects on cardiac electrophysiology in mice.

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