Preparation of Plasma Membrane Vesicles from Bone Marrow Mesenchymal Stem Cells for Potential Cytoplasm Replacement TherapyLi-qun Xu 1, Mei-jia Lin 1, Yun-pan Li 1, Shuang Li 1, Shao-jun Chen 1, Chi-ju Wei 1
1Multidisciplinary Research Center, Shantou University
Age-related diseases are associated with multiple defects in components of the cytoplasm. Here, we present a protocol to prepare plasma membrane vesicles from bone marrow mesenchymal stem cells. This technique could potentially be used as a means of cytoplasm replacement therapy to ameliorate or even reverse age-associated phenotypes.