Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle SynthesisJorge T. Dias 1, Gustav Svedberg 1, Mats Nystrand 2, Helene Andersson-Svahn 1, Jesper Gantelius 1
1Division of Proteomics and Nanobiotechnology, Science for Life Laboratory, KTH Royal Institute of Technology, 2Global Research and Development, Thermo Fisher Scientific IDD
In this work, a protocol for signal enhancement of nanoprobe-based biosensing is presented. The protocol is based on the reduction of chloroauric acid onto the surface of existing nanoprobes that consist of gold, silver, silica or iron-oxide nanoparticles.