Ground State Depletion Super-resolution Imaging in Mammalian CellsRose E. Dixon 1, Oscar Vivas 1, Karen I. Hannigan 1, Eamonn J. Dickson 1
1Department of Physiology and Membrane Biology, University of California School of Medicine, Davis
This article outlines a protocol for the detection of one or more plasma and/or intracellular membrane proteins using Ground State Depletion (GSD) super-resolution microscopy in mammalian cells. Here, we discuss the benefits and considerations of using such approaches for the visualization and quantification of cellular proteins.
