Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

DOI :

10.3791/224-v

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July 4th, 2007

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17,684 Views

Christine Beeton¹, Adriana Garcia¹, K. George Chandy¹

¹Department of Physiology and Biophysics, University of California, Irvine (UCI)

Chapters

This video demonstrates the induction and clinical scoring of an animal model of multiple sclerosis: chronic-relapsing experimental autoimmune encephalomyelitis in DA rats. The disease, induced by immunizing rats with an emulsion containing whole rat spinal cord and complete Freund's adjuvant, presents clinical signs resembling the human disease.

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