Results: Evaluation and Analysis of Active and Inactive Compounds in the Competition Binding Assay
6:35
Conclusion
TRANSCRIÇÃO
The overall goal of the cell-based Assay is to identify molecules that bind to a G protein coupled receptor. Based on their capability to compete with a fluorescently-labeled ligand for binding to the receptor. Competition binding assay can suppor
Sign in or start your free trial to access this content
A flow cytometry-based cellular binding assay is described that is primarily used as a screening tool to identify compounds that inhibit the binding of a fluorescently labeled CXC chemokine ligand 12 (CXCL12) to the CXC chemokine receptor 4 (CXCR4).