Results: iHep Mediated Repopulation of LRG Mice Liver
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Conclusion
TRANSCRIÇÃO
This method have answered key questions in the field, such as how to generate a human liver chimeric mouse model, familial hypercholesterolemia. The main advantage of this technique is that it allows performing drug tests in in vivo. This techniqu
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Here, we present a protocol to generate a human liver chimeric mouse model of familial hypercholesterolemia using human induced pluripotent stem cell-derived hepatocytes. This is a valuable model for testing new therapies for hypercholesterolemia.