Results: Key Features of Genetic Manipulations of Mammary Epithelial Cells Based on Intraductal Injection of Ad-Cre
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Conclusion
Transcrição
This protocol will help researchers generate a new type of mouse model to recapitulate human breast cancer development from different subsets of mammary epithelial cells. This technique allows researchers to generate breast cancer mouse models in
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The goal of this protocol is to describe a new breast cancer modeling approach based on the intraductal injection of Cre-expressing adenovirus into mouse mammary glands. This approach allows both cell-type- and organ-specific manipulation of oncogenic events in a temporally controlled manner.