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Enhanced Viability for Ex vivo 3D Hydrogel Cultures of Patient-Derived Xenografts in a Perfused Microfluidic Platform

5.9K Views

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12:12 min

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December 5th, 2020

DOI :

10.3791/60872-v

December 5th, 2020

•
5,906 Views
1Department of BioSciences, Rice University, 2Mimetas US Inc, 3Department of Genitourinary Medical Oncology Research, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, 4Mimetas B.V., 5Department of Bioengineering, Rice University, 6Department of Diagnostic and Biomedical Sciences, The University of Texas Health Science Center, 7Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center

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Keywords Patient derived Xenografts
PDX
3D Hydrogel Cultures
Microfluidic Platform
Ex Vivo Culture
Tumor Cells
Drug Screening
Heterogeneous Systems
Co cultures
Stroma
Endothelium
Immune Cells
Tumor Architecture
Cell Loading
Cell Alignment
Tumor Dissociation
Cell Counting
Cell Density
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