Results: Generating Patient-Derived Ovarian Cancer Organoids from Patient Tumors, Ascites, and Pleural Fluid Samples
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Conclusion
TRANSCRIÇÃO
Patient drive organoid models genetically and functionally represent their parent tumors and thus are reliable models for studying novel therapeutics and complex biologic processes in ovarian cancer. By recapitulating clonal heterogeneity, the tum
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Patient-derived organoids (PDO) are a three-dimensional (3D) culture that can mimic the tumor environment in vitro. In high-grade serous ovarian cancer, PDOs represent a model to study novel biomarkers and therapeutics.