Name: Oxidation and Reduction of Organic Molecules
Uploaded: 2023-04-30T10:09:20
Description: Learn by watching this video about Oxidation and Reduction of Organic Molecules at JoVE.com

Living organisms break down organic molecules in a series of reactions to generate energy. Many of these reactions are oxidation-reduction reactions or redox reactions.
Oxidation is the removal of electrons from an atom, while reduction is the addition of electrons. Because the number of electrons in a reaction is conserved, oxidation and reduction half-reactions always occur in pairs.
Inside cells, when a molecule gains an electron, it often accepts a proton from its surroundings. This addition of hydrogen is called hydrogenation, and the molecule is reduced. Conversely, when a molecule loses hydrogens, this is a dehydrogenation, and the molecule is oxidized.
Protons and electrons can be transferred to electron-carrying molecules, including coenzymes.
For example, in the dehydrogenation of succinate to fumarate, electrons and protons are transferred to the coenzyme FAD, reducing it to FADH2. The reduced FADH2 further transfers the electrons through the electron transport chain and is oxidized back to FAD.

oxidation and reduction of organic molecules

Energy production within a cell involves many coordinated chemical pathways. Most of these pathways are combinations of oxidation and reduction reactions, which occur at the same time. An oxidation reaction strips an electron from an atom in a compound, and the addition of this electron to another compound is a reduction reaction. Because oxidation and reduction usually occur together, these pairs of reactions are called redox reactions.
The removal of an electron from a molecule, results in a decrease in potential energy in the oxidized compound. However, the electron (sometimes as part of a hydrogen atom) does not remain unbonded in the cytoplasm of a cell. Rather, the electron is shifted to a second compound, reducing the second compound. The shift of an electron from one compound to another removes some potential energy from the first compound (the oxidized compound) and increases the potential energy of the second compound (the reduced compound). The transfer of electrons between molecules is important because most of the energy stored in atoms and used to fuel cell functions is in the form of high-energy electrons. The transfer of energy in the form of high-energy electrons allows the cell to transfer and use energy in an incremental fashion&#8212;in small packages rather than in a single, destructive burst.
In living systems, a small class of compounds functions as electron shuttles: they bind and carry high-energy electrons between compounds in biochemical pathways. The principal electron carriers we will consider are derived from the B vitamin group and are derivatives of nucleotides. These compounds can be easily reduced (that is, they accept electrons) or oxidized (they lose electrons). Nicotinamide adenine dinucleotide (NAD) is derived from vitamin B3, niacin. NAD+ is the oxidized form of the molecule; NADH is the reduced form of the molecule after it has accepted two electrons and a proton (which together are the equivalent of a hydrogen atom with an extra electron).
This text is adapted from <a href="https://openstax.org/books/biology-2e/pages/7-1-energy-in-living-systems">Openstax, Biology 2e, Section 7.1 Energy in Living Systems </a>

Learn by watching this video about Oxidation and Reduction of Organic Molecules at JoVE.com

Oxidation and Reduction of Organic Molecules

Energy production within a cell involves many coordinated chemical pathways. Most of these pathways are combinations of oxidation and reduction reactions, ...