The benzylic position describes the position of a carbon atom attached directly to a benzene ring. Benzene by itself does not undergo oxidation. In contrast, the benzylic carbon is quite reactive in the presence of strong oxidizing agents such as KMnO₄ or H₂CrO₄. Therefore, alkylbenzenes are readily oxidized to benzoic acid, irrespective of the type of alkyl groups.

Halogen and nitro substituents on a benzene ring remain unaffected by these oxidizing agents.

When more than one alkyl side chain is attached to the benzene ring, each gets oxidized to carboxyl groups.

The only condition required for benzylic oxidation is to have at least one hydrogen at the benzylic position. This means that tert-butylbenzene, which lacks benzylic hydrogen, does not undergo oxidation.

Benzene is also unreactive towards catalytic hydrogenation. A typical alkene double bond attached to a benzene ring can be selectively reduced under specific conditions without affecting the other functional groups. For example, in the selective reduction of 4-phenyl-3-buten-2-one to 4-phenyl-2-butanone, the benzene ring and ketone group remain unaffected.