JoVE Encyclopedia of Experiments
A subscription to JoVE is required to view this content. Sign in or start your free trial.
Overview
Encyclopedia of Experiments
In this video, we describe the procedure to deliver human-derived tumor cells into the cisterna magna of a mouse’s brain. The orthotopic mouse model can be used to study metastatic spread of cancer to the cranial meninges.
This article has been published
Video Coming Soon
Source: Law, V. et al. A Murine Ommaya Xenograft Model to Study Direct-Targeted Therapy of Leptomeningeal Disease. J. Vis. Exp. (2021)
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved