Induction of Experimental Autoimmune Encephalomyelitis in a Mouse Model

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Encyclopedia of Experiments

Induction of Experimental Autoimmune Encephalomyelitis in a Mouse Model

Overview

The video demonstrates the induction of experimental autoimmune encephalomyelitis in a mouse model by injecting a combination of myelin oligodendrocyte glycoproteins and inactivated Mycobacterium tuberculosis. The model enables researchers to study disease mechanisms and test therapeutic interventions.

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Source: Barthelmes, J. et al., Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues. J. Vis. Exp. (2016)