Establishing an Infection Model Through Microinjection of Gastric Organoids with Pathogenic Bacteria

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Encyclopedia of Experiments

Establishing an Infection Model Through Microinjection of Gastric Organoids with Pathogenic Bacteria

Overview

This video demonstrates a method to establish a gastric organoid infection model by microinjecting gastric pathogen Helicobacter pylori into the lumen of the organoids. This model helps in studying infection-induced changes in gastric cells.

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Source: Bartfeld, S. et al. Organoids as Model for Infectious Diseases: Culture of Human and Murine Stomach Organoids and Microinjection of Helicobacter Pylori. J. Vis. Exp.(2015).