Neuromuscular Ultrasound of the Median Nerve at the Carpal Tunnel

Summary

The present protocol describes a technique for the standardization of median nerve ultrasound in cases of suspected carpal tunnel syndrome.

Abstract

The use of neuromuscular ultrasound greatly enhances the evaluation of carpal tunnel syndrome as an adjunct diagnostic tool as it provides dynamic and structural information about the median nerve and its surrounding anatomy. Neuromuscular ultrasound aids in diagnostic accuracy (when used with electrodiagnostic testing) and offers etiologic information as a non-invasive, painless, cost-effective, and radiation-free imaging technology that can be easily carried out at the bedside for immediate interpretation. Neuromuscular ultrasound has the limitation of subjectivity, and the need for training and experience will affect the interpretation of results. This article describes a basic practical guide to visualizing the median nerve using neuromuscular ultrasound in a step-by-step manner to aid in the evaluation of carpal tunnel syndrome. Even though the use of ultrasound in the assessment of median nerve entrapment has been long established, there has been no recognized standard protocol. The present protocol aims to provide clear and concise instructions to describe a standard technique to visualize the median nerve through diagnostic ultrasound.

Introduction

Neuromuscular ultrasound (NMUS) is an increasingly popular method that may be used in conjunction with electrodiagnostic and clinical information in order to diagnose, prognosticate, and guide injection procedures in patients with neuromuscular conditions¹. Anatomical structures such as nerves, muscles, bones, and tendons can be identified with high-resolution ultrasound that can refine a diagnosis and provide structural etiology when present. Visualizing the median nerve in the carpal tunnel space-the site of the most common entrapment neuropathy-is one of the most mainstream uses of neuromuscular ultrasound. The rationale fo....

Protocol

The protocol follows the guidelines of the Wake Forest School of Medicine Research and Ethics committee, and informed written consent was obtained following IRB approval prior to imaging. Any patient with carpal tunnel syndrome who had abnormal nerve conduction studies of the median nerve was appropriate for ultrasound imaging. Individuals with no symptoms of carpal tunnel and normal nerve conduction studies were excluded from the study. A high-end multi-purpose ultrasound machine, equipped with a 15 MHz linear array transducer (see Table of Materials) was used in the present study.

1. Visualizing the median nerve at ....

Results

Typical appearance of a peripheral nerve on the ultrasound
Peripheral nerves consist of hypoechoic (dark) nerve fascicles surrounded by a thick hyperechoic rim of the epineurium. Each nerve fascicle is also surrounded by a thin layer of hyperechoic perineurium, giving rise to a honeycomb appearance in the peripheral nerve in the cross-sectional view (Figure 2A). In the sagittal view, peripheral nerves demonstrate an uninterrupted fascicular pattern with alternating hyp.......

Discussion

As ultrasound visualization is a subjective process and operator dependent, it is critical to follow an organized approach in order to accurately determine parameters, including cross-sectional area, mobility, echogenicity, and vascularity. The most important steps include holding the probe perpendicular to the nerve while the patient is in the correct position. In addition, visualizing the nerve throughout its course proximally and distally to the area of entrapment allows for discovering further pathology or othe.......

Materials

Name	Company	Catalog Number	Comments
GE CARES LOGIQ insite exc ultrasound Machine	any	6066032WX0
High-frequency (12 to 18 MHz) linear array transducer	GE
Ultrasound Gel	Aquasonic