이 작업은 2022년 "Tianfu Qingcheng Plan" Tianfu Science and Technology Leading Talents Project(Chuan Qingcheng No. 1090), National TCM Clinical Excellent Talents Training Program(National TCM Renjiao Letter[2022] No. 1), Chengdu University of Traditional Chinese Medicine 병원의 "100 Talent Plan" 프로젝트(병원 사무실[2021] 42), 쓰촨성 중국 전통 의학 관리 과학 연구 특집(2021MS093, 2021MS539, 2023MS608)을 참조하십시오.

임상시험 프로토콜은 청두 중의과대학 병원 호흡기내과 임상연구승인위원회(Clinical Research Approval Committee)의 검토 및 승인을 받았습니다. KY 2022010)입니다.
1. 장비 준비
<ol><li>일회용 멸균 침술 바늘(크기 0.25mm x 40mm), 뜸 스틱(크기 1.2cm x 1.2cm), 의료용 멸균 면봉, 요오드포 면봉, 라이터 및 여러 개의 60mm x 60mm 판지를 준비합니다( 그림 1 참조).</...

복부 팽만으로 COPD를 완화하는 따뜻한 침술과 뜸

<ol>
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COPD로 인한 복부 팽만의 발병 기전이 완전히 밝혀지지 않아 새로운 치료법과 약물 개발을 방해한다는 것은 잘 알려진 사실입니다. 최근에는 온열 침술과 뜸이 복부 팽만과 결합된 COPD에 널리 적용되고 있습니다. 온열 침술과 뜸의 치료 기전은 주로 침의 효과, 뜸 가온 효과 및 바늘 몸체의 열전도 효과(31)이다. 뜸은 경혈의 국소 온난화에 초점을 맞춥니다. 국소 특이적 수용체, 열?...

만성 폐쇄성 폐질환(COPD)은 호흡기의 흔한 만성 소모성 질환입니다. COPD 환자는 주로 만성 기침과 가래로 나타나며, 질병이 점진적으로 진행되고 폐 기능이 점진적으로 저하됩니다. 이 질병은 만성 폐 심장 질환, 호흡 부전 및 질병 말기의 심부전으로 인해 복잡해질 수 있으며, 이는 환자의 삶의 질에 심각한 영향을 미칩니다. 장내 미생물군의 변화는 COPD1의 질병 진행과 관련이 있는 것으로 보고되었습니다. 폐 증상 외에도 안정 COPD 환자의 40.31%가 복부 팽만감을 호소했다. 복부 팽만감은 폐 증상 악화, COPD 급성 악화 빈도 증가, 안정적인 COPD 환자의 삶의 질 저하에 상당한 영향을 미칠 수 있다 2,3. COPD에서 복부 팽만의 원인은 다음과 같은 것을 포함할 수 있는 다인자로 간주됩니다: (1) 박테리아의 미생물 불균형; (2) 복수는 복강 내 압력을 증가시킵니다. (3) 전해질 장애; (4) 우심부전 및 간 또는 소화관의 울혈; (5) 장시간 침상 안정4; (6) 약물5 및 기계적 환기6.
일부 한의학자들은 COPD의 발병 과정이 4가지 상태의 과정이라고 제안했다.(1) 폐 기 결핍; (2) 비장 기 결핍; (3) 신장 기 결핍; (4) 음양(陰陽)결핍 7,8. 비장이 이동과 변형에 실패하고 위가 약해져서 수용이 되지 않으면 복부 팽만감이 발생할 수 있으며, 이는 화학 물질의 부족으로 인해 근육이 얇아지고 약화될 수 있다9. 현재 COPD의 임상치료에 일반적으로 사용되는 약물로는 기관지 확장제, 글루코코르티코이드, 항생제 및 기타 약물이 있다10. 증상으로 치료되는 경우가 많은 복부 팽만과 결합된 COPD에 대한 표준화된 치료 프로토콜을 명시한 지침은 없습니다.
한의학에서 따뜻한 침술과 뜸은 기(氣)가 경락을 준설하고, 혈액 순환을 활성화하고, 혈액 정체를 제거하고, 양(陽)을 따뜻하게 하고, 냉기를 없애기 위해 결핍을 보충하도록 유도할 수 있습니다. 항산화 물질을 생산하여 면역 체계 스트레스 반응을 촉진하고 혈액 순환을 개선할 수 있는 조절 역할을 할 수 있습니다11,12. 온열 침술과 뜸은 경추 척추증(cervical spondylosis)13, 무릎 관절염(two arthritis)14, 월경통(dysmenorrhea)15, 변비(distipation)16, 과민성 대장 증후군(irritable bowel syndrome)17 등을 치료하는 데 사용할 수 있다. 실험적 연구에 따르면 침술은 뇌-장 축을 조절하여 복부 팽만감을 완화할 수 있다18. 뜸과 침 치료는 복부 팽창을 현저히 감소시키는데,19 이는 혈장 프로스타글란딘 E2와 혈장 및 위 점막 조직의 가스트린 수치 조절을 통해 발휘될 수 있다20. 한편, 온열 침술과 뜸은 기능성 소화불량의 증상을 개선한다는 점에서 운동요법과 가짜 침술보다 우수하다21. 침술은 횡격막을 강화하고 호흡 근육의 피로를 완화할 뿐만 아니라 이산화탄소 저류와 저산소증을 개선하며 호흡 부전을 예방하고 완화할 수 있다22. 온열 침 치료와 뜸은 안정적인 COPD 환자의 폐 기능, 임상 증상 및 삶의 질을 개선한다23,24.
"폐는 대장과 내외적 관계에 있다"는 한의학 이론에 따르면 본 연구에서 사용하는 온열 침술과 뜸 치료는 위장 기능의 회복을 촉진하고 폐 기능과 삶의 질을 향상시키는 것을 목표로 합니다. 온열 침술과 뜸은 매우 효과적이고, 시행하기 쉬우며, 저렴한 형태의 전통 한의학 치료법이다. 결론적으로, 복부 팽만으로 COPD를 완화하기 위해 온열 침술과 뜸을 적절하게 사용하는 방법에 대한 표준 프로토콜을 제안할 필요가 있습니다. 이 글에서는 복부 팽만으로 COPD를 완화하기 위해 온열 침 치료와 뜸 치료를 적절하게 조작하는 방법을 설명합니다.

<table border="1" fo:keep-together.within-page="1" fo:keep-with-next.within-page="always">
	<tbody>
		<tr>
			<td>Moxa stick</td>
			<td>Dr. Moxi</td>
			<td>N/A</td>
			<td>size: 1.2 cm x 1.2 cm</td>
		</tr>
		<tr>
			<td>Disposable sterile acupuncture needle</td>
			<td>HWATO</td>
			<td>2001-0020</td>
			<td>size:&#160; 0.25 mm x 40 mm</td>
		</tr>
		<tr>
			<td>Iodophor swabs</td>
			<td>BEIJIAER</td>
			<td>20162140536</td>
			<td></td>
		</tr>
		<tr>
			<td>Cardboard</td>
			<td>In-house</td>
			<td>In-house</td>
			<td>size: 60 mm x 60 mm&#160;</td>
		</tr>
	</tbody>
</table>

a preliminary study on warm acupuncture and moxibustion for treating chronic obstructive pulmonary disease with abdominal distension

대부분의 COPD 환자는 복부 팽만감이 복합적으로 나타나며, 이는 폐 증상, 급성 악화 빈도 및 COPD 환자의 삶의 질에 부정적인 영향을 미치는 것으로 나타났습니다. 온열 침 치료와 뜸은 복부 팽만과 결합된 COPD 환자의 증상 완화에 효과적인 것으로 나타났습니다. 온열 침술과 뜸은 매우 효과적이고, 시행하기 쉬우며, 저렴한 형태의 전통 한의학 치료법이다. 온열 침술과 뜸의 표준화된 관행은 복부 팽만과 결합된 COPD의 치료에 매우 중요합니다. 구체적인 단계에는 증후군 감화 치료를 통해 침을 씌우기에 적합한 경혈을 선택하고 De-qi 후 약 30분 동안 뜸을 위한 적절한 길이의 뜸 스틱을 선택하는 것이 포함됩니다. 치료 과정은 일주일 동안 지속됩니다. COPD 평가 테스트(CAT) 점수와 복부 팽만 시각적 아날로그 척도(VAS)와 같은 지표가 구체적으로 평가됩니다. 이 글은 복부 팽만과 결합된 COPD를 완화하기 위해 온열 침술과 뜸의 조작을 표준화하는 방법을 명확하게 설명할 것입니다.

Chronic obstructive pulmonary disease (COPD) is a common chronic consumptive disease of the respiratory system. Patients with COPD mainly manifest in chronic cough and sputum, with the progressive development of the disease and gradual decline in lung function. The disease may be complicated by chronic pulmonary cardiac disease, respiratory failure, and heart failure in the later stages of the disease, which seriously affects the quality of life of patients. It is reported that alterations in gut microbiota are associated with disease progression in COPD1. In addition to pulmonary symptoms, 40.31% of patients with stable COPD reported abdominal distention. Abdominal distension can have a significant impact on worsening pulmonary symptoms, increasing the frequency of acute exacerbations of COPD, and impairing the quality of life of patients with stable COPD2,3. The causes of abdominal distension in COPD are considered to be multifactorial which may include as follows: (1) dysbiosis of bacteria; (2) ascites, which increases intra-abdominal pressure; (3) electrolyte disturbances; (4) right heart failure and congestion of the liver or digestive tract; (5) prolonged bed rest4; (6) medications5 and mechanical ventilation6.
Some Chinese medicine scholars have proposed that the development process of COPD is the process of four states:(1) lung qi deficiency; (2) spleen qi deficiency; (3) kidney qi deficiency; (4) Yin and yang deficiency7,8. If the spleen fails to transport and transform and the stomach is weak and unable to receive, abdominal distension may occur, which in turn can lead to muscle thinning and weakness due to the lack of chemical sources9. At present, the drugs commonly used in the clinical treatment of COPD include bronchodilators, glucocorticoids, antibiotics, and other drugs10. There are no guidelines specifying standardized treatment protocols for COPD combined with abdominal distention, which is often treated symptomatically.
Warm acupuncture and moxibustion in traditional Chinese medicine can guide Qi to dredge the meridians, invigorate blood circulation, remove blood stasis, replenish deficiency to warm yang, and dissipate cold. They can produce antioxidant substances and thus play a regulatory role, which can promote immune system stress response and improve blood circulation11,12. Warm acupuncture and moxibustion can be used to treat cervical spondylosis13, knee arthritis14, dysmenorrhea15, constipation16, irritable bowel syndrome17, and so on. Experimental studies have turned out that acupuncture can relieve abdominal distension by regulating the brain-gut axis18. Acupuncture combined with moxibustion significantly reduces abdominal distention19, which may be exerted through the regulation of plasma prostaglandin E2 and gastrin levels in plasma and gastric mucosal tissues20. Meanwhile, warm acupuncture and moxibustion are superior to prokinetics and sham acupuncture in terms of improving the symptoms of functional dyspepsia21. Acupuncture can strengthen the diaphragm and relieve respiratory muscle fatigue, as well as improve carbon dioxide retention, and hypoxia, and prevent and relieve respiratory failure22. Warm acupuncture and moxibustion improve lung function, clinical symptoms, and quality of life in patients with stable COPD23,24.
According to the theory of Chinese medicine that &#34;The lung stands in interior-exterior relationship with the large intestine&#34;, the warming acupuncture and moxibustion treatment used in this study aim to promote the recovery of gastrointestinal function and improve pulmonary function and quality of life. Warm acupuncture and moxibustion are highly effective, easy to perform, and inexpensive forms of traditional Chinese medicine treatments. In conclusion, it is necessary to propose a standard protocol on how to properly operate the use of warm acupuncture and moxibustion to relieve COPD with abdominal distension. This article describes how to properly manipulate the use of warm acupuncture and moxibustion treatment to relieve COPD with abdominal distension.

저자 스포트라이트: 복부 팽만감을 동반한 만성 폐쇄성 폐질환에 대한 효과적인 한의학 치료법 

복부 팽만성을 동반한 만성폐쇄성폐질환 치료를 위한 온열침술과 뜸에 관한 예비연구

We propose a standardized manipulation of warm acupuncture and moxibustion for treating chronic obstructive pulmonary disease, or COPD, combined with abdominal distention. This method can help answer key questions in the field of COPD with abdominal distention. The manual advantages of warm acupuncture and moxibustion include the method's high effectiveness in operation, ease of performance, and affordability.These forms of traditional Chinese medicine treatments can benefit many patients. Our laboratory will be committed to studying the basic mechanism of warm acupuncture and moxibustion to alleviate COPD with abdominal distension. Our future work will focus on establishing more intelligent manipulations of warming acupuncture, and moxibustion.

일반 조건 복부 팽만감과 결합된 COPD 환자 총 12명(표 1)을 관찰군과 대조군으로 나누었으며, 각 군에 각각 6명의 환자가 있었다. 모두 ''만성 폐쇄성 폐질환에 대한 1차 진료 지침(2018)''29 의 진단 기준을 충족했으며 복부 팽만감이 있었습니다. 대조군에는 유사 침이 투여되었습니다. 관찰군과 동일한 경혈을 선택하고 이 경혈 옆 2.5cm의 피부에 수직으로 ?...

Watch this Scientific Journal Video about An Effective Traditional Chinese Medicinal Treatment for Chronic Obstructive Pulmonary Disease with Abdominal Distension at JoVE.com

여기에서는 복부 팽만으로 만성 폐쇄성 폐질환(COPD)을 치료하기 위한 온열 침술과 뜸을 적절하게 조작하기 위한 프로토콜을 제시합니다.

Most patients with COPD have a combination of abdominal distension, which has been shown to adversely affect pulmonary symptoms, frequency of acute ...

우리는 만성 폐쇄성 폐 질환(COPD)과 복부 팽만감을 병행하기 위한 온열 침술과 뜸의 표준화된 조작을 제안합니다. 이 방법은 복부 팽창이 있는 COPD 분야의 주요 질문에 답하는 데 도움이 될 수 있습니다. 온열 침술과 뜸의 수동 장점에는 방법의 높은 작동 효과, 성능 용이성 및 경제성이 포함됩니다.이러한 형태의 한의학 치료는 많은 환자에게 도움이 될 수 있습니다. 우리 연구실은 복부 팽만으로 인한 COPD를 완화하기 위한 온열 침술과 뜸의 기본 기전을 연구하기 위해 노력할 것입니다. 우리의 향후 연구는 온난화, 침술 및 뜸에 대한 보다 지능적인 조작을 확립하는 데 중점을 둘 것입니다.

복부 팽만성을 동반한 만성폐쇄성폐질환 치료를 위한 온열침술과 뜸에 관한 예비연구

Abstract