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This manuscript presents a comprehensive protocol to evaluate the three-dimensional (3D) movement of maxillary posterior teeth with clear aligners using digital model superimposition, an invaluable tool in orthodontics and dentofacial orthopedics.
Since the introduction of Invisalign by Align Technology, Inc. in 1999, questions and debates have persisted regarding the precision of Invisalign (clear aligner) therapy, particularly when compared to the use of traditional fixed appliances. This becomes particularly significant in cases involving anteroposterior, vertical, and transverse corrections, where precise comparisons are of paramount importance. To address these inquiries, this study introduces a meticulously devised protocol, placing a primary emphasis on digitally superimposing the movement of maxillary posterior teeth to facilitate accurate analysis. The sample included 25 patients who had completed their first series of Invisalign (clear) aligners. Four maxillary digital models (pre-treatment, post-treatment, ClinCheck-initial, and final models) were digitally superimposed using the palate rugae and dentitions as stable references. A software combination was used for model superimposition and tooth segmentation. Transformation matrices then expressed the differences between the achieved and predicted tooth positions. Thresholds for clinically relevant differences were at ±0.25 mm for linear displacement and ±2° for rotation. Differences were assessed using Hotelling's T-squared tests with Bonferroni correction. The mean differences in rotation (2.036° ± 4.217°) and torque (-2.913° ± 3.263°) were significant statistically and clinically, with p-values of 0.023 and 0.0003 respectively. De-rotation of premolars and torque control for all posterior teeth were less predictable. All mean differences for the linear measurements were statistically and clinically insignificant, except that the first molars seemed slightly (0.256 mm) more intruded than their predicted position. The clear aligner system appears to meet its prediction for most translational tooth movements and mesial-distal tipping in maxillary posterior teeth for non-extraction cases with mild to moderate malocclusions.
In 1999, digitally fabricated removable orthodontic appliances were made commercially available by Align (Align Technology Inc., Tempe, AZ). Originally, this system was designed to solve non-growing cases with mild to moderate crowding or close small spaces as an aesthetic alternative to traditional fixed edgewise appliances. With decades of improvements in computer-aided design and manufacturing (CAD/CAM), dental materials, and treatment planning, clear aligner therapy (CAT) has since been used to treat over 10 million patients with various malocclusions worldwide1. A recent retrospective study suggested that CAT is as effective as fixed appli....
This study received ethical approval from the Institutional Review Board at the University of British Columbia (No. H19-00787). To uphold confidentiality, all samples utilized in the study underwent de-identification procedures. Furthermore, prior to their inclusion in the research, informed consent was appropriately obtained from all participating patients.
NOTE: Each participant contributed four maxillary digital models, which encompassed the following:
A minimum sample size of 24 cases was required to detect an effect change of 0.6° for the average tip and torque angles, with an 80% power and an alpha of 0.0523. The inclusion criteria were as follows: (1) full permanent dentition through the first molars, (2) Class I malocclusions, or less than 2 mm Class II /III malocclusions with spacing, or mild to moderate crowding that had undergone non-extraction Invisalign treatment, (3) completion of the first series of Invisalign aligners at least,.......
The palatal rugae have a unique configuration at adolescence; they remain constant during growth, are authentic markers for personal identification, and are considered stable anatomic references for maxillary model superimposition24,25,26,27. Dai et al. used this method to compare the achieved and predicted tooth movement of maxillary first molars and central incisors with clear aligners after .......
This work was financed by the International Align Research Award Program (Align Technology Inc., Tempe, AZ). However, the funding source had no involvement in the conduct of the research and/or preparation of the article. We would like to thank Dr. Sandra Tai and Dr. Samuel Tam for their generous support for providing the Invisalign cases and Nikolas Krstic for his professional support for statistic analyses.
....Name | Company | Catalog Number | Comments |
CloudCompare | GPL software | Version 2.11 | open-source software (https://www.cloudcompare.net/) |
Meshmixer software | Autodesk, Inc. | ||
Rhinoceros 5.0 | Robert McNeel & Associates | Version 5.0 |
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