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Abstract

Medicine

推拿对大鼠模型的镇痛作用,压迫背根神经节疼痛

Published: July 14th, 2023

DOI:

10.3791/65535

1Department of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, 2Rehabilitation Medicine Department, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, 3Department of Tuina, Shuguang Hospital of Shanghai University of Traditional Chinese Medicine

* These authors contributed equally

Abstract

神经性疼痛是一种普遍存在的疾病,影响 6.9%-10% 的人口,由各种病因引起的神经损伤引起,例如腰椎间盘突出症、椎管狭窄和椎间孔狭窄。虽然推拿作为一种传统的中国手法疗法,在临床上显示出治疗神经性疼痛的镇痛作用,但其潜在的神经生物学机制尚不清楚。动物模型对于阐明推拿的基本原理至关重要。在这项研究中,我们提出了一种标准化的推拿方案,用于压迫背根神经节 (DRG) 的大鼠,其中包括通过将不锈钢棒插入椎间孔来诱导 DRG 压迫,在受控环境中以特定的位置、强度和频率参数进行推拿操作,并评估推拿治疗的行为和组织病理学结果。本文还讨论了该研究的潜在临床意义和局限性,并提出了未来推拿研究的方向。

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