Alexander Hergovich

UCL Cancer Institute

Research Area

Biology

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2013

Other Publications

Article	Year
Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL. Nature cell biology\| PubMed ID: 12510195	2003
Relevance of nuclear and cytoplasmic von hippel lindau protein expression for renal carcinoma progression. The American journal of pathology\| PubMed ID: 12937142	2003
Regulation of NDR2 protein kinase by multi-site phosphorylation and the S100B calcium-binding protein. The Journal of biological chemistry\| PubMed ID: 15037617	2004
Human NDR kinases are rapidly activated by MOB proteins through recruitment to the plasma membrane and phosphorylation. Molecular and cellular biology\| PubMed ID: 16135814	2005
Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3. Molecular and cellular biology\| PubMed ID: 16314523	2005
NDR kinases regulate essential cell processes from yeast to humans. Nature reviews. Molecular cell biology\| PubMed ID: 16607288	2006
The human tumour suppressor LATS1 is activated by human MOB1 at the membrane. Biochemical and biophysical research communications\| PubMed ID: 16674920	2006
Priming-dependent phosphorylation and regulation of the tumor suppressor pVHL by glycogen synthase kinase 3. Molecular and cellular biology\| PubMed ID: 16847331	2006
Centrosome-associated NDR kinase regulates centrosome duplication. Molecular cell\| PubMed ID: 17317633	2007
Mammalian NDR protein kinases: from regulation to a role in centrosome duplication. Biochimica et biophysica acta\| PubMed ID: 17881309	2008
Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors. Cellular signalling\| PubMed ID: 18555663	2008
NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis. Current biology : CB\| PubMed ID: 19062280	2008
Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin. Molecular biology of the cell\| PubMed ID: 19073886	2009
Mammalian NDR/LATS protein kinases in hippo tumor suppressor signaling. BioFactors (Oxford, England)\| PubMed ID: 19484742	2009
VHL loss causes spindle misorientation and chromosome instability. Nature cell biology\| PubMed ID: 19620968	2009
The MST1 and hMOB1 tumor suppressors control human centrosome duplication by regulating NDR kinase phosphorylation. Current biology : CB\| PubMed ID: 19836237	2009
TAZ-mediated crosstalk between Wnt and Hippo signaling. Developmental cell\| PubMed ID: 20412766	2010
Ablation of the kinase NDR1 predisposes mice to the development of T cell lymphoma. Science signaling\| PubMed ID: 20551432	2010
Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases. Molecular and cellular biology\| PubMed ID: 20624913	2010
Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability. Molecular and cellular biology\| PubMed ID: 21262772	2011
MOB control: reviewing a conserved family of kinase regulators. Cellular signalling\| PubMed ID: 21539912	2011
Downstream of human NDR kinases: impacting on c-myc and p21 protein stability to control cell cycle progression. Cell cycle (Georgetown, Tex.)\| PubMed ID: 21593588	2011
MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis. Molecular and cellular biology\| PubMed ID: 21730291	2011
Mammalian Hippo signalling: a kinase network regulated by protein-protein interactions. Biochemical Society transactions\| PubMed ID: 22260677	2012
Hippo signalling in the G2/M cell cycle phase: lessons learned from the yeast MEN and SIN pathways. Seminars in cell & developmental biology\| PubMed ID: 22525225	2012
YAP-Hippo signalling downstream of leukemia inhibitory factor receptor: implications for breast cancer. Breast cancer research : BCR\| PubMed ID: 23216692	2012